A 839977 CAS: 870061-27-1
MF: C19H14Cl2N6O
MW: 413.26
A potent antagonist P2X7.

A 839977 (CAS 870061-27-1)

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Alternate Names: 1-(2,3-Dichlorophenyl)-N-[[2-(2-pyridinyloxy)phenyl]methyl]-1H-tetrazol-5-amine; 1-(2,3-Dichlorophenyl)-N-[2-(2-pyridinyloxy)benzyl]-1H-tetrazol-5-amine
Application A 839977 is A 839977 is a potent antagonist P2X7
CAS 등록번호: 870061-27-1
분자량: 413.26
분자식: C19H14Cl2N6O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* 참조분석증명서대량의 측정 데이터(함수량포함).

A 839977 is a potent P2X7 antagonist that blocks BzATP-evoked calcium influx at P2X7 receptors. This compound displays antinociceptive properties in rat and mice models of inflammatory pain.

Physical State :
Solid
용해도 :
Soluble in DMSO (100 mM).
저장 :
Store at 4° C
비등점 :
~604.9° C at 760 mmHg (Predicted)
밀도 :
~1.5 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
53325875
MDL Number :
MFCD19690959
SMILES :
C1=CC=C(C(=C1)CNC2=NN=NN2C3=C(C(=CC=C3)Cl)Cl)OC4=CC=CC=N4

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