Date published: 2026-5-15

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(8R,12R,11R,16RS)-Misoprostol Acid-d5

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Application:
(8R,12R,11R,16RS)-Misoprostol Acid-d5 is a deuterated version of PGE1 with agonist activity mediated by EP2, EP3, and EP4
Molecular Weight:
373.54
Molecular Formula:
C21H31D5O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(8R,12R,11R,16RS)-Misoprostol Acid-d5 is a deuterated analog of misoprostol acid, characterized by the substitution of hydrogen atoms with deuterium at specific positions within the molecule. This alteration enhances the molecule′s stability against metabolic degradation, making it particularly useful in research settings for detailed pharmacokinetic and metabolic studies. The deuterium atoms, being heavier than hydrogen, form stronger bonds with carbon, which are less susceptible to enzymatic breakage due to the kinetic isotope effect. This property allows researchers to track the compound more accurately as it undergoes metabolic processes, providing clearer insights into how it behaves within biological systems. The use of (8R,12R,11R,16RS)-Misoprostol Acid-d5 in research helps in elucidating the metabolic pathways and degradation products of the active non-deuterated compound, which is crucial for understanding its biosynthesis and interaction with biological systems. Such studies are essential for advancing knowledge in biochemical research, aiding in the development of methodologies for studying similar compounds. Furthermore, this compound facilitates the exploration of enzyme-substrate interactions at a molecular level, offering significant contributions to the fields of biochemistry and molecular biology without any direct application in clinical settings.


(8R,12R,11R,16RS)-Misoprostol Acid-d5 References

  1. The nursing services in Wales: midwifery.  |  . 1978. Nurs Mirror. 147: vi-viii. PMID: 250046
  2. Misoprostol: a prostaglandin E1 analogue.  |  Garris, RE. and Kirkwood, CF. 1989. Clin Pharm. 8: 627-44. PMID: 2507215
  3. Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial.  |  Graham, DY., et al. 1988. Lancet. 2: 1277-80. PMID: 2904006

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(8R,12R,11R,16RS)-Misoprostol Acid-d5, 500 µg

sc-217513
500 µg
$263.00