5,7-Dichloro-8-quinolinol (CAS 773-76-2)

건강 상태 :

Solid

용해도 :

5% IN DIOXANE; CLEAR TO SLIGHTLY HAZY,YELLOW OR GREEN SOLUTION.Soluble in benzene, acetone. Slightly soluble in acetic acid. Readily soluble in sodium and potassium hydroxides and in acids, forming solutions. Very slightly soluble in: Ethanol Chloroform.

저장 :

Store at room temperature

녹는점 :

178-180° C (lit.)

비등점 :

~354.7° C at 760 mmHg (Predicted)

밀도 :

~1.5 g/cm³ (Predicted)

굴절률 :

n²⁰_D 1.70 (Predicted)

IC50 :

Arachidonate 5-lipoxygenase: IC₅₀ = 3.6 µM (human); Arachidonate 12-lipoxygenase: IC₅₀ = 1.9 µM (human); Arachidonate 15-lipoxygenase, type II: IC₅₀ = 28 µM (human); Arachidonate 15-lipoxygenase: IC₅₀ = 2.4 µM (human); Kappa opioid receptor: IC₅₀ = 4.56 µM (human); Streptococcus sp. ′group A′: EC₅₀50 = 258 nM (Streptococcus sp. ′group A′); Streptococcus: EC₅₀50 = 3306 nM (Streptococcus); Beta-galactosidase: EC₅₀50 = >31.5 µM (Escherichia coli); Streptokinase A: EC₅₀50 = 148 nM (Streptococcus pyogenes serotype M1); Delta opioid receptor: IC₅₀ >32 µM (human)

pK 값 :

pK_a: 2.30, pK_b: 7.20

WGK 독일 :

3

RTECS :

VC5350000

PubChem CID :

Merck 색인 :

14: 2175

MDL 번호 :

MFCD00006786

EC 번호 :

212-258-3

Beilstein 기재 :

153606

SMILES :

C1=CC2=C(C(=C(C=C2Cl)Cl)O)N=C1