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3′′-Hydroxy Simvastatin Acid, Sodium Salt is a compound that functions as an inhibitor of HMG-CoA reductase, an enzyme involved in the biosynthesis of cholesterol. It acts by competitively binding to the active site of the enzyme, preventing the conversion of HMG-CoA to mevalonate, a key step in cholesterol production. This inhibition ultimately leads to a decrease in intracellular cholesterol levels. 3′′-Hydroxy Simvastatin Acid, Sodium Salt may upregulate the expression of LDL receptors on the surface of hepatocytes, leading to increased uptake and clearance of LDL cholesterol from the bloodstream. These combined mechanisms result in a reduction of circulating LDL cholesterol levels, which may be useful for studying cholesterol metabolism.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Hydroxy Simvastatin Acid, Sodium Salt, 2.5 mg | sc-216638 | 2.5 mg | $448.00 | |||
3-Hydroxy Simvastatin Acid, Sodium Salt, 10 mg | sc-216638A | 10 mg | $1290.00 |