(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid (CAS 100828-16-8)

건강 상태 :

Solid

용해도 :

Soluble in 1 N NaOH (at 100 mM), and water (to 100 mM). Insoluble in ethanol.

저장 :

Desiccate at room temperature

비등점 :

546.7° C at 760 mmHg

밀도 :

1.41 g/cm³

굴절률 :

n²⁰_D 1.53

IC50 :

Glutamate NMDA receptor: IC₅₀ = 28 nM (rat); Glutamate [NMDA] receptor subunit epsilon 1: IC₅₀ = 72 nM (mouse); Glutamate [NMDA] receptor subunit 3A: IC₅₀ = 72 nM (mouse); Glutamate [NMDA] receptor subunit epsilon 2: IC₅₀ = 72 nM (mouse); Glutamate [NMDA] receptor subunit epsilon 3: IC₅₀ = 72 nM (mouse)

Ki 데이타 :

Glutamate [NMDA] receptor subunit epsilon 3: K_i= 131 nM (rat); Glutamate [NMDA] receptor subunit epsilon 1: K_i= 131 nM (rat); Glutamate [NMDA] receptor subunit epsilon 2: K_i= 131 nM (rat); Glutamate [NMDA] receptor subunit epsilon 4: K_i= 131 nM (rat)

pK 값 :

pK_a: 1.89 (Predicted), pK_b: 9.42 (Predicted)

WGK 독일 :

3

PubChem CID :

MDL 번호 :

MFCD00055136

SMILES :

C1CN(CC(N1)C(=O)O)CCCP(=O)(O)O