Molecular structure of 2-Hydroxy Imipramine, CAS Number: 303-70-8
2-Hydroxy Imipramine (CAS 303-70-8)
Alternate Names:
5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepin-2-ol;2-Hydroxyimipramine; G 33679
Application:
2-Hydroxy Imipramine is a metabolite of Imipramine
CAS Number:
303-70-8
Molecular Weight:
296.41
Molecular Formula:
C19H24N2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-Hydroxy Imipramine is a metabolite of Imipramine. The transformation is part of the phase I metabolism that typically involves oxidation, reduction, or hydrolysis reactions to increase the solubility of lipophilic substances, making them easier to excrete. The introduction of a hydroxyl group to imipramine results in the formation of 2-Hydroxy Imipramine, altering its chemical properties such as solubility, polarity, and potentially its interactions with biological molecules. This process is mediated by enzymes such as the cytochrome P450 family, which plays a role in the metabolism of various substances. 2-Hydroxy Imipramine interacts with neurotransmitters, such as serotonin and norepinephrine, that could lead to changes in biochemical processes.
2-Hydroxy Imipramine (CAS 303-70-8) References
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- Antiarrhythmic plasma-concentration range of imipramine against ventricular premature depolarizations. | Giardina, EG., et al. 1983. Clin Pharmacol Ther. 34: 284-9. PMID: 6883904
- Phase I metabolism of imipramine by microsomes of small intestine in comparison with metabolism by liver microsomes. | Christ, W., et al. 1983. Naunyn Schmiedebergs Arch Pharmacol. 323: 176-82. PMID: 6888570
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Hydroxy Imipramine, 2 mg | sc-209186C | 2 mg | $255.00 | |||
2-Hydroxy Imipramine, 5 mg | sc-209186 | 5 mg | $357.00 | |||
2-Hydroxy Imipramine, 10 mg | sc-209186A | 10 mg | $520.00 | |||
2-Hydroxy Imipramine, 25 mg | sc-209186B | 25 mg | $1224.00 | |||
2-Hydroxy Imipramine, 50 mg | sc-209186D | 50 mg | $2244.00 |