Molecular structure of 2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran, CAS Number: 1951-26-4
2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran (CAS 1951-26-4)
Alternate Names:
(2-Butyl-benzofuran-3-yl)-(4-hydroxy-3,5-diiodo-phenyl)-methanone; USP Amiodarone Related Compound D
Application:
2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran is an analog of Amiodarone
CAS Number:
1951-26-4
Purity:
≥98%
Molecular Weight:
546.14
Molecular Formula:
C19H16I2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran is an analog of the anti-arrhythmic compound Amiodarone (sc-210799). 2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran results from O-dealkylation of the parent compound. Analogs of Amiodarone including 2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran were demonstrated to competitively inhibit 5′-T4 (thyroxine) deiodination.
2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran (CAS 1951-26-4) References
- Structure-effect relationships of amiodarone analogues on the inhibition of thyroxine deiodination. | Ha, HR., et al. 2000. Eur J Clin Pharmacol. 55: 807-14. PMID: 10805058
- Synthesis and preliminary characterization of a novel antiarrhythmic compound (KB130015) with an improved toxicity profile compared with amiodarone. | Carlsson, B., et al. 2002. J Med Chem. 45: 623-30. PMID: 11806713
- Identification and characterization of small molecule inhibitors of a plant homeodomain finger. | Wagner, EK., et al. 2012. Biochemistry. 51: 8293-306. PMID: 22994852
- Synthesis of 2‐n butyl 3‐(3, 5‐125diiodo 4‐(N, N‐diethylamino 2‐ethoxybenzoyl)) benzofuran hydrochloride (125I amiodarone) | Sion, R. 1985. Journal of Labelled Compounds and Radiopharmaceuticals. 22(8): 799-806.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran, 1 g | sc-209121 | 1 g | $260.00 |