Molecular structure of 15-Keto-prostaglandin F2α, CAS Number: 35850-13-6
15-Keto-prostaglandin F2α (CAS 35850-13-6)
Application:
15-Keto-prostaglandin F2α is a PGF2α metabolite shown to be part of goldfish and Atlantic salmon pheromones
CAS Number:
35850-13-6
Molecular Weight:
352.5
Molecular Formula:
C20H32O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
15-Keto-prostaglandin F2α is the first metabolite of PGF2α, biosynthesized by 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). This compound is believed to be one of the critical components in the postovulatory pheromone for goldfish and Atlantic salmon, and has been shown to stimulate their olfactory receptors. 15-Keto-prostaglandin F2α is reportedly 10-folds less active than PGF2α at decreasing rabbit intraocular pressure; however, prostaglandin metabolites may have important biological functions due to an increased half-life under physiological conditions.
15-Keto-prostaglandin F2α (CAS 35850-13-6) References
- 15-hydroxyprostaglandin dehydrogenase. A review. | Hansen, HS. 1976. Prostaglandins. 12: 647-79. PMID: 184496
- F-series prostaglandin function as sex pheromones in the Korean salamander, Hynobius leechii. | Eom, J., et al. 2009. Comp Biochem Physiol A Mol Integr Physiol. 154: 61-9. PMID: 19457459
- Marked differential effects of prostanoid metabolites on rabbit intraocular pressure. | Woodward, DF., et al. 1989. Ophthalmic Res. 21: 428-35. PMID: 2626239
- Metabolomics study on primary dysmenorrhea patients during the luteal regression stage based on ultra performance liquid chromatography coupled with quadrupole‑time‑of‑flight mass spectrometry. | Fang, L., et al. 2017. Mol Med Rep. 15: 1043-1050. PMID: 28098892
- F prostaglandins function as potent olfactory stimulants that comprise the postovulatory female sex pheromone in goldfish. | Sorensen, PW., et al. 1988. Biol Reprod. 39: 1039-50. PMID: 3219377
- The use of tritiated prostaglandins in metabolism studies. I: Evaluation of the kinetic isotope effect in the prostaglandin dehydrogenase reactions. | Moussard, C., et al. 1986. Prostaglandins. 31: 489-500. PMID: 3715057
- Electrophysiological and endocrinological evidence that F-series prostaglandins function as priming pheromones in mature male Atlantic salmon (Salmo salar parr. | Moore, A. and c,. 1996. J Exp Biol. 199: 2307-16. PMID: 9320226
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
15-Keto-prostaglandin F2α, 1 mg | sc-201234 | 1 mg | $80.00 | |||
15-Keto-prostaglandin F2α, 10 mg | sc-201234A | 10 mg | $638.00 |