Molecular structure of 1-Methylnicotinamide chloride, CAS Number: 1005-24-9
1-Methylnicotinamide chloride (CAS 1005-24-9)
See product citations (2)
Alternate Names:
3-Carbamyl-1-methylpyridinium Chloride
Application:
1-Methylnicotinamide chloride is a metabolite of nicotinamide that serves a role in modulating cellular redox status and controlling signaling and transcriptional events.
CAS Number:
1005-24-9
Purity:
≥98%
Molecular Weight:
172.61
Molecular Formula:
C7H9N2OCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-Methylnicotinamide chloride is a metabolite of nicotinamide that serves a role in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide chloride, as a niacin metabolite, is excreted via the urinary system. 1-Methylnicotinamide chloride demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability.
1-Methylnicotinamide chloride (CAS 1005-24-9) References
- Direct determination of the stoichiometry of charge transfer complexes. | Teller, DC. and Deranleau, DA. 1976. Biochim Biophys Acta. 421: 416-9. PMID: 1252475
- Crystal structure of the ion pair 1-methyl-3-carbamidopyridinium N-acetyl-L-tryptophanate, a model for 1-substituted nicotinamide-protein charge-transfer completes. | Ash, RP., et al. 1977. J Am Chem Soc. 99: 4471-5. PMID: 140887
- Quantitation of the niacin metabolites 1-methylnicotinamide and l-methyl-2-pyridone-5-carboxamide in random spot urine samples, by ion-pairing reverse-phase HPLC with UV detection, and the implications for the use of spot urine samples in the assessment of niacin status. | Creeke, PI. and Seal, AJ. 2005. J Chromatogr B Analyt Technol Biomed Life Sci. 817: 247-53. PMID: 15686992
- Fluorescence Spectrometric Determination of Drugs Containing α-Methylene Sulfone/Sulfonamide Functional Groups Using N-Methylnicotinamide Chloride as a Fluorogenic Agent. | Elokely, KM., et al. 2011. Int J Anal Chem. 2011: 840178. PMID: 21647288
- Nanomechanical sensing of the endothelial cell response to anti-inflammatory action of 1-methylnicotinamide chloride. | Kolodziejczyk, AM., et al. 2013. Int J Nanomedicine. 8: 2757-67. PMID: 23946648
- Effects of 1-Methylnicotinamide (MNA) on Exercise Capacity and Endothelial Response in Diabetic Mice. | Przyborowski, K., et al. 2015. PLoS One. 10: e0130908. PMID: 26115505
- 1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis. | Blazejczyk, A., et al. 2016. J Exp Clin Cancer Res. 35: 110. PMID: 27412454
- Pharmacokinetic Profile of 1-Methylnicotinamide Nitrate in Rats. | Szafarz, M., et al. 2017. J Pharm Sci. 106: 1412-1418. PMID: 28153597
- Chromate reduction by rabbit liver aldehyde oxidase. | Banks, RB. and Cooke, RT. 1986. Biochem Biophys Res Commun. 137: 8-14. PMID: 2941018
- Safety of 1-methylnicotinamide chloride (1-MNA) as a novel food pursuant to Regulation (EC) No 258/97. | ,., et al. 2017. EFSA J. 15: e05001. PMID: 32625296
- Determination of nicotinamide and metabolic products in urine by high-performance liquid chromatography. | McKee, RW., et al. 1982. J Chromatogr. 230: 309-17. PMID: 6213629
- Determination of Nicotinic Acid and Metabolites in Urine, Cosmetics, and Pharmaceuticals by High-Performance Liquid Chromatography with Novel Electrochemical Detection | LH Wang. 2014. Analytical Letters, 2016 - Taylor & Francis.
- Simultaneously covalent and ionic bridging towards antifouling of GO-imbedded nanocomposite hollow fiber membranes | Yu Pan Tang,a Jing Xiong Chan,a Tai Shung Chung,*a Martin Weber,b Claudia Staudtc and Christian Maletzkod. 2015. Journal of Materials Chemistry A. Issue 19, 2015.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Methylnicotinamide chloride, 1 g | sc-237583 | 1 g | $135.00 | |||
1-Methylnicotinamide chloride, 5 g | sc-237583A | 5 g | $318.00 | |||
1-Methylnicotinamide chloride, 25 g | sc-237583B | 25 g | $791.00 |