Villin Antibody (BDID2C3): sc-66022
- Villin Antibody (BDID2C3) is a mouse monoclonal IgG1 κ, cited in 12 publications, provided at 200 µg/ml
- raised against purified full length native Villin of chicken origin
- recommended for detection of Villin of mouse, rat, human and avian origin by WB, IP, IF, IHC(P) and ELISA; non cross-reactive with breast cancer
- See Villin (1D2C3): sc-58897 for Villin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Villin Antibody (BDID2C3) for WB and IHC(P) applications. This reagent is now offered in a bundle with Villin Antibody (BDID2C3) (see ordering information below).
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Villin Antibody (BDID2C3) is a mouse monoclonal IgG1 antibody that detects Villin in mouse, rat, human, and avian species through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Villin is a crucial actin-binding protein primarily found in the brush border of absorptive epithelial cells, where Villin plays a significant role in maintaining the structure and function of microvilli. Villin (BDID2C3) antibody recognizes a protein essential for organizing the cytoskeleton and regulating the assembly and disassembly of actin filaments, which is vital for cellular processes such as absorption, signaling, and motility. Villin′s ability to respond to calcium ions adds another layer of regulation, allowing for adaptation to various physiological conditions. Anti-Villin antibody (BDID2C3) detects a protein present in different tissues, underscoring Villin′s importance in both muscle and non-muscle cells, making anti-Villin antibody (BDID2C3) a valuable marker for studying cellular dynamics and pathologies related to cytoskeletal dysfunction.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Villin Antibody (BDID2C3) References:
- Villin-like actin-binding proteins are expressed ubiquitously in Arabidopsis. | Klahre, U., et al. 2000. Plant Physiol. 122: 35-48. PMID: 10631247
- Villin enhances hepatocyte growth factor-induced actin cytoskeleton remodeling in epithelial cells. | Athman, R., et al. 2003. Mol Biol Cell. 14: 4641-53. PMID: 12937273
- Association of villin with phosphatidylinositol 4,5-bisphosphate regulates the actin cytoskeleton. | Kumar, N., et al. 2004. J Biol Chem. 279: 3096-110. PMID: 14594952
- Villin severing activity enhances actin-based motility in vivo. | Revenu, C., et al. 2007. Mol Biol Cell. 18: 827-38. PMID: 17182858
- Villin immunohistochemistry is a reliable method for diagnosing microvillus inclusion disease. | Shillingford, NM., et al. 2015. Am J Surg Pathol. 39: 245-50. PMID: 25517957
- Villin induces microvilli growth and actin redistribution in transfected fibroblasts. | Friederich, E., et al. 1989. Cell. 59: 461-75. PMID: 2680107
- Plant Villin Headpiece Domain Demonstrates a Novel Surface Charge Pattern and High Affinity for F-Actin. | Miears, HL., et al. 2018. Biochemistry. 57: 1690-1701. PMID: 29444403
- Mouse intestinal tuft cells express advillin but not villin. | Esmaeilniakooshkghazi, A., et al. 2020. Sci Rep. 10: 8877. PMID: 32483224
- Moderate binding of villin headpiece protein to C3N3 nanosheet reveals the suitable biocompatibility of this nanomaterial. | Luo, Y., et al. 2023. Sci Rep. 13: 13783. PMID: 37612444
- Calcium dependence of villin-induced actin depolymerization. | Walsh, TP., et al. 1984. Biochemistry. 23: 6099-102. PMID: 6525347
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Villin Antibody (BDID2C3) | sc-66022 | 200 µg/ml | $322.00 | |||
Villin Antibody (BDID2C3): m-IgG Fc BP-HRP Bundle | sc-551947 | 200 µg Ab; 10 µg BP | $361.00 |