Tyrphostin AG 537

身体の状態 :

Solid

溶解度 :

Soluble in DMSO (10 mg/ml).

保存方法 :

Store at -20° C

融点 :

349.84° C (Predicted)

沸騰点 :

901.65° C at 760 mmHg (Predicted)

密度 :

1.46 g/cm³ (Predicted)

屈折率 :

n²⁰_D 1.71 (Predicted)

IC50 :

Epidermal growth factor receptor kinase autophosphorylation : IC₅₀ = 400 nM; Antiplasmodial activity against Plasmodium falciparum 3D7 : IC₅₀ = 1.58 µM; Antiplasmodial activity against Plasmodium falciparum HB3 : IC₅₀ = 1.58 µM; Dynamin I: IC₅₀ = 1.7 µM (human); Plasmodium falciparum: IC₅₀ = 2.5 µM

pK値 :

pK_a: 8.51 (Predicted)

WGKドイツ :

3

PubChem CID :

MDL番号 :

MFCD00236440

SMILES :

C1=CC(=C(C=C1/C=C(/C(=O)NCCCNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N)\\C#N)O)O