SIB 1893 (CAS 6266-99-5)

外観 :

Crystalline

身体の状態 :

Solid

溶解度 :

Soluble in DMSO (100 mM). Insoluble in water.

保存方法 :

Desiccate at 4° C

融点 :

43.4-43.9° C

沸騰点 :

307.28° C at 760 mmHg (Predicted)

密度 :

1.07 g/cm³ (Predicted)

屈折率 :

n²⁰_D 1.65 (Predicted)

IC50 :

mGluR-5: IC₅₀ = 0.29 µM (human); Glutamate-induced Ca2+ response: IC₅₀ = 0.29 µM (hmGluR5a/L38-20 cells); Quisqualate-induced InsP accumulation: IC₅₀ = 2.3 µM (hmGluR5a/L38-20 cells); Photinus pyralis luciferase: IC₅₀ = 4.3 µM; mGluR-1a: IC₅₀ >100 µM (human)

Ki データ :

mGluR-5: K_i= 0.29 µM (human); mGluR-4: K_i= 26 µM (human); mGluR-7: K_i>100 µM (human); mGluR-2: K_i>100 µM (human); mGluR-6: K_i>100 µM (human)

pK値 :

pK_b: 5.42 (Predicted)

WGKドイツ :

3

RTECS :

UT5810210

輸送 :

Not available for sale outside of the United States.

PubChem CID :

MDL番号 :

MFCD02262120

SMILES :

CC1=CC=CC(=N1)/C=C/C2=CC=CC=C2