Penicillin G potassium salt (CAS 113-98-4)

外観 :

Powder

身体の状態 :

Solid

溶解度 :

Soluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform.

保存方法 :

Store at 4° C

融点 :

214-217° C (lit.)

密度 :

1.36 g/cm³

屈折率 :

n²⁰_D ~1.66 (Predicted)

光学活性 :

α20_D 285±15, c = 1 in water

IC50 :

Penicillin-binding protein 1A: IC₅₀ = 0.002 µg/ml (Streptococcus pneumoniae serotype 4 ); Penicillin-binding protein 2B: IC₅₀ = 0.007 µg/ml (Streptococcus pneumoniae serotype 4 ); Penicillin-binding protein 2x: IC₅₀ = 0.007 µg/ml (Streptococcus pneumoniae serotype 4 ); Bacillus subtilis: IC₅₀ = 1.56 µg/ml; Staphylococcus aureus: IC₅₀ = 1.56 µg/ml

Ki データ :

Beta-lactamase TEM: K_i= 20 µM (Escherichia coli); Solute carrier family 22 member 8: K_i= 52.8 µM (rat); OAT3: K_i= 97.6 µM (human); Solute carrier family 22 member 6: K_i= 328 µM (mouse); Solute carrier family 22 member 6: K_i= 418 µM (rat)

WGKドイツ :

2

RTECS :

XH9700000

PubChem CID :

Merck 索引 :

14: 7094

MDL番号 :

MFCD00036193

EC番号 :

204-038-0

Beilstein レジストリ :

3832841

SMILES :

CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[K+]