Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Phosphodiesterases (PDEs), also designated cyclic nucleotide phosphodiesterases, are important for the downregulation of the intracellular level of the second messenger cyclic adenosine monophosphate (cAMP) by hydrolyzing cAMP to 5′AMP. The PDE family contains proteins that serve tissue-specific roles in the regulation of lipolysis, glycogenolysis, myocardial contractility and smooth muscle relaxation. PDE6D, also designated phosphodiesterase 6D cGMP-specific rod δ, is a retina-specific oligomer composed of two catalytic chains (α and β), an inhibitory chain (γ) and the δ chain. It interacts with RPGR, ARL2 and ARL3, and contains 150 amino acids, which are unusually well conserved, with only a few conservative substitutions in human, cow, mouse and rat PDE6D. The PDE6D protein contains two N-linked glycosylation sites.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.