p115 Antibody (5D6): sc-20021

p115 Antibody (5D6) is a mouse monoclonal IgG1 antibody that detects p115 in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). p115, also known as transcytosis-associated protein (TAP), tethering factor, or vesicle docking protein (VDP), plays a crucial role in membrane trafficking, which is essential for maintaining cellular homeostasis and facilitating communication between organelles. p115 is primarily localized to the Golgi complex, where p115 is involved in the transport of vesicles from the endoplasmic reticulum to the Golgi apparatus. p115′s localization ensures the proper delivery of proteins and lipids, which are necessary for various cellular functions, including secretion and membrane recycling. p115 interacts with other proteins such as giantin and GM130, which are key players in membrane tethering events, further underscoring p115′s importance in the secretory and endocytic pathways. p115′s ability to bind transport vesicles prior to membrane fusion highlights p115′s role as a general factor in vesicular transport, making p115 an essential component in the intricate network of cellular trafficking. Anti-p115 antibody (5D6) serves as an invaluable tool for researchers studying membrane dynamics and protein transport mechanisms.

The preferred p115 antibody is p115 Antibody (H-11): sc-48363.