Oct-2 Antibody (D-12): sc-365116
- Oct-2 Antibody (D-12) is a mouse monoclonal IgM κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 435-463 at the C-terminus of Oct-2 of human origin
- recommended for detection of Oct-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine
- TransCruz reagent for ChIP application (sc-365116 X, 200 µg/0.1 ml)
- See Oct-2 (PT2): sc-56822 for Oct-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Oct-2 Antibody (D-12) for WB applications. This reagent is now offered in a bundle with Oct-2 Antibody (D-12) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Oct-2 Antibody (D-12) is a mouse monoclonal IgM antibody that detects Oct-2 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Oct-2 (D-12) antibody plays a crucial role in studying the regulation of gene expression, particularly in the immune system, where Oct-2 is essential for activating immunoglobulin gene transcription in B cells. Oct-2 is primarily located in the nucleus, where Oct-2 binds to specific DNA sequences known as octamer motifs, which are vital for transcribing immunoglobulin genes and other tissue-specific genes. Oct-2′s interaction with various transcriptional coactivators, such as OBF1, enhances regulatory capacity, making Oct-2 a key player in B lymphocyte differentiation and function. Understanding Oct-2′s function and localization is important for elucidating immune response mechanisms and B cell-related disorders. Oct-2 (D-12) monoclonal antibody serves as an invaluable tool for researchers studying these processes and the broader implications of transcriptional regulation in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oct-2 Antibody (D-12) | sc-365116 | 200 µg/ml | $322.00 | |||
Oct-2 Antibody (D-12): m-IgGκ BP-HRP Bundle | sc-552336 | 200 µg Ab; 40 µg BP | $361.00 | |||
Oct-2 (D-12) Neutralizing Peptide | sc-365116 P | 100 µg/0.5 ml | $69.00 | |||
Oct-2 Antibody (D-12) X | sc-365116 X | 200 µg/0.1 ml | $322.00 |