Norfloxacin (CAS 70458-96-7)
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In the field of microbiology, norfloxacin is a key agent used to study bacterial DNA replication processes, as it targets DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA supercoiling and segregation. Its mechanism of action provides valuable insight into the inhibition of bacterial growth and proliferation, aiding in the understanding of antibiotic action at the molecular level. Furthermore, norfloxacin is utilized in environmental biology to examine the impact of antibiotics on microbial communities, particularly in aquatic systems where pharmaceutical contaminants are of concern. It is also a reference molecule in the development of new diagnostic methods to detect bacterial resistance to fluoroquinolones. In addition to its direct applications in research, the photochemical properties of norfloxacin make it a suitable candidate for studies in photochemistry, where it is used to investigate the effects of light on drug stability and activity.
Norfloxacin (CAS 70458-96-7) References
- Investigation of β-cyclodextrin-norfloxacin inclusion complexes. Part 2. Inclusion mode and stability studies. | Mendes, C., et al. 2015. Expert Rev Anti Infect Ther. 13: 131-40. PMID: 25488143
- Pharmacokinetics of norfloxacin after intravenous, intramuscular and subcutaneous administration to rabbits. | Marín, P., et al. 2018. J Vet Pharmacol Ther. 41: 137-141. PMID: 28603857
- Determination of norfloxacin in urine and pharmaceutical samples using terbium doped zinc sulphide nanomaterials-sensitized fluorescence method. | Kaur, B., et al. 2019. Spectrochim Acta A Mol Biomol Spectrosc. 214: 261-268. PMID: 30785046
- Determination of Norfloxacin Using a Tetraoxocalix[2]arene[2]triazine Covalently Functionalized Multi-walled Carbon Nanotubes Modified Electrode. | Dang, J., et al. 2019. Anal Sci. 35: 979-985. PMID: 31080199
- Photocatalytic oxidation of norfloxacin by Zn0.9Fe0.1S supported on Ni-foam under visible light irradiation. | Zhang, G., et al. 2019. Chemosphere. 230: 406-415. PMID: 31112863
- Assessment of norfloxacin degradation induced by plasma-produced ozone using surface-enhanced Raman spectroscopy. | Huang, Q., et al. 2020. Chemosphere. 238: 124618. PMID: 31470309
- The pharmacokinetics of norfloxacin in the aged. | MacGowan, AP., et al. 1988. J Antimicrob Chemother. 22: 721-7. PMID: 3209530
- Synthesis, characterization and antimicrobial activity of norfloxacin based acetohydrazides. | Walayat, K., et al. 2020. Pak J Pharm Sci. 33: 855-860. PMID: 32863262
- Comparison of visible light driven H2O2 and peroxymonosulfate degradation of norfloxacin using Co/g-C3N4. | Zhang, W., et al. 2021. Chemosphere. 262: 127955. PMID: 33182160
- Toward broader applications of iron ore waste in pollution control: Adsorption of norfloxacin. | Fang, N., et al. 2021. J Hazard Mater. 418: 126273. PMID: 34329023
- Highly efficient photocatalytic degradation of norfloxacin via Bi2Sn2O7/PDIH Z-scheme heterojunction: Influence and mechanism. | Yin, N., et al. 2022. J Hazard Mater. 436: 129317. PMID: 35739807
- Norfloxacin: review of safety studies. | Corrado, ML., et al. 1987. Am J Med. 82: 22-6. PMID: 3605158
- Paeoniflorin combined with norfloxacin ameliorates drug-resistant Streptococcus suis infection. | Li, J., et al. 2022. J Antimicrob Chemother. 77: 3275-3282. PMID: 36173390
- Photosensitization by norfloxacin is a function of pH. | Bilski, P., et al. 1996. Photochem Photobiol. 64: 496-500. PMID: 8806228
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Norfloxacin, 10 g | sc-215586 | 10 g | $125.00 |