MIP-T3 Antibody (F-12): sc-166336
- MIP-T3 Antibody (F-12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 524-560 near the C-terminus of MIP-T3 of human origin
- recommended for detection of MIP-T3 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for MIP-T3 Antibody (F-12) for WB applications. This reagent is now offered in a bundle with MIP-T3 Antibody (F-12) (see ordering information below).
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MIP-T3 Antibody (F-12) is a mouse monoclonal IgG1 antibody that detects MIP-T3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MIP-T3 plays a crucial role in cellular signaling by interacting with tumor necrosis factor receptor-associated factors (TRAFs), particularly TRAF3, which is essential for regulating various cellular processes including proliferation, differentiation, and apoptosis. The interaction between MIP-T3 and TRAF3 is facilitated by the coiled-coil TRAF-N domain of TRAF3, allowing MIP-T3 to recruit TRAF3 to microtubules, thereby linking TRAF3 to the cytoskeletal network. This association is significant as it may provide a novel mechanism for the spatial regulation of TRAF3, influencing its signaling capabilities and cellular localization. MIP-T3 (F-12) antibody is an invaluable tool for researchers studying the dynamics of TRAF3 and its role in cellular signaling pathways, offering insights into the underlying mechanisms of various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MIP-T3 Antibody (F-12) | sc-166336 | 200 µg/ml | $322.00 | |||
MIP-T3 Antibody (F-12): m-IgG Fc BP-HRP Bundle | sc-540081 | 200 µg Ab; 10 µg BP | $361.00 | |||
MIP-T3 (F-12) Neutralizing Peptide | sc-166336 P | 100 µg/0.5 ml | $69.00 |