LRCH4 Antibody (E-1): sc-390018

LRCH4 Antibody (E-1) is a mouse monoclonal IgG2a antibody that detects LRCH4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LRCH4, also known as leucine-rich repeats and calponin homology (CH) domain containing 4, LRN, LRRN1, or LRRN4, is a 683 amino acid protein that plays a crucial role in cellular signaling and cytoskeletal organization. LRCH4 includes a carboxy-terminal region that may function as a membrane anchor, facilitating cell-to-cell interactions, while the amino-terminal region is rich in leucine repeats, which are believed to be involved in ligand binding. Additionally, the calponin homology domain within LRCH4 mediates interactions with actin and various cytoskeletal and signaling molecules, underscoring LRCH4′s importance in maintaining cellular integrity and facilitating communication between cells. The gene encoding LRCH4 is located on human chromosome 7, a region that contains over 1,000 genes and represents nearly 5% of the human genome, highlighting LRCH4′s potential significance in a wide array of biological processes. Anti-LRCH4 antibody (E-1) is an essential tool for researchers investigating the functional roles of LRCH4 in various cellular contexts.

The preferred LRCH4 antibody is LRCH4 Antibody (A-9): sc-377441.