Molecular structure of L-3,3′,5-Triiodothyronine, Sodium Salt, CAS Number: 55-06-1
L-3,3′,5-Triiodothyronine, Sodium Salt (CAS 55-06-1)
Alternate Names:
T3, Na; Triostat; Cytomel; Tertroxin
Application:
L-3,3′,5-Triiodothyronine, Sodium Salt is a compound that stimulates respiratory activity at the mitochondrial level
CAS Number:
55-06-1
Purity:
≥99%
Molecular Weight:
672.96
Molecular Formula:
C15H11I3NNaO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
L-3,3′,5-Triiodothyronine, sodium salt, known as T3 in its salt form, is extensively used in research focused on thyroid hormone action and metabolism. As an active form of thyroid hormone, it is pivotal for studies investigating the regulation of metabolic rate, development, and differentiation within cells. Scientists leverage L-3,3′,5-Triiodothyronine, sodium salt to explore its influence on gene expression, particularly genes that are responsive to thyroid hormone levels in the body. In vitro, this compound facilitates the investigation of thyroid hormone receptors and the biochemical pathways they regulate, which has implications for understanding metabolic disorders and certain cardiovascular diseases. Additionally, T3 sodium salt is utilized in research concerning developmental biology, as thyroid hormones are vital for normal growth and maturation in vertebrates.
L-3,3′,5-Triiodothyronine, Sodium Salt (CAS 55-06-1) References
- Inhibition of cyclin E-cyclin-dependent kinase 2 complex formation and activity is associated with cell cycle arrest and withdrawal in oligodendrocyte progenitor cells. | Ghiani, C. and Gallo, V. 2001. J Neurosci. 21: 1274-82. PMID: 11160398
- Expression of the green fluorescent protein in the oligodendrocyte lineage: a transgenic mouse for developmental and physiological studies. | Yuan, X., et al. 2002. J Neurosci Res. 70: 529-45. PMID: 12404507
- c-Myc-dependent transcriptional regulation of cell cycle and nucleosomal histones during oligodendrocyte differentiation. | Magri, L., et al. 2014. Neuroscience. 276: 72-86. PMID: 24502923
- Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. | Liu, J., et al. 2015. J Neurosci. 35: 352-65. PMID: 25568127
- Interactions of thyroid hormone and tricyclic antidepressants on rat brain beta-adrenoceptor function. | Catto, LC., et al. 1987. Arch Toxicol Suppl. 11: 247-9. PMID: 2820355
- Contribution of non-ADH pathways to ethanol oxidation in hepatocytes from fed and hyperthyroid rats. Effect of fructose and xylitol. | Vind, C. and Grunnet, N. 1985. Biochem Pharmacol. 34: 655-61. PMID: 3156600
- Influence of thyroid hormones on the number of nucleoli and the degree of polyploidy in rat liver. | Schlatterer, B. and Paul, HS. 1974. Acta Anat (Basel). 90: 563-72. PMID: 4460678
- Effect of thyroid hormones on the activities of hepatic alcohol metabolizing enzymes. | Moreno, F., et al. 1979. Biochem Biophys Res Commun. 89: 806-12. PMID: 486198
- Variations in the glycosylation of the collagen synthesized by chick embryo cartilage. Effects of development and several hormones. | Blumenkrantz, N. and Prockop, DJ. 1970. Biochim Biophys Acta. 208: 461-6. PMID: 5506576
- Hepatic microsomal ethanol-oxidizing system (MEOS): increased activity following propylthiouracil administration. | Moreno, F., et al. 1981. Alcohol Clin Exp Res. 5: 85-91. PMID: 7013553
- Alterations of hepatic alcohol metabolizing enzyme activities due to thyroid hormones. | Moreno, F., et al. 1980. Adv Exp Med Biol. 132: 109-15. PMID: 7424701
- Developmental and hormonal regulation of the Xenopus liver-type arginase gene. | Xu, Q., et al. 1993. Eur J Biochem. 211: 891-8. PMID: 7916684
- Effect of 3,3'-di-iodothyronine and 3,5-di-iodothyronine on rat liver mitochondria. | Lanni, A., et al. 1993. J Endocrinol. 136: 59-64. PMID: 8381457
- Regulation of beta myosin heavy chain, c-myc and c-fos proto-oncogenes in thyroid hormone-induced hypertrophy of the rat myocardium. | Green, NK., et al. 1993. Clin Sci (Lond). 84: 61-7. PMID: 8382136
Inhibitor of:
Na+/K+-ATPase α3.Activator of:
ACADS, AQP9, ATP1AL1, c-Erb-A α, COX7c, EFR3B, EG330305, Gm239, GRIP-1, HNF-6, Midnolin, MUP12, MYH7, Na+/K+-ATPase β1, NPT2, OAT2, OLIG2, OPN1SW, ORMDL2, OTTMUSG00000002040, OTTMUSG00000002045, OTTMUSG00000005723, PDE4B, PLC β3, SMYD1, SNAP 25, Spot 14, TAF7L, TNRC18, TR α, Trypsin X3, V-ATPase A1, and V-ATPase B2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-3,3′,5-Triiodothyronine, Sodium Salt, 250 mg | sc-205725 | 250 mg | $115.00 |