HspBP1 Antibody (D-2): sc-166315
- HspBP1 Antibody (D-2) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 290-321 near the C-terminus of HspBP1 of human origin
- recommended for detection of HspBP1 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HspBP1 Antibody (D-2) for WB applications. These reagents are now offered in bundles with HspBP1 Antibody (D-2) (see ordering information below).
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SEE ALSO...
HspBP1 Antibody (D-2) is a mouse monoclonal IgG2b antibody that detects HspBP1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HspBP1, a crucial member of the eukaryotic protein family known as nucleotide exchange factors for Hsp70, plays a significant role in cellular protein homeostasis by facilitating the maturation of the cystic fibrosis transmembrane conductance regulator (CFTR). HspBP1 is primarily localized in heart and skeletal muscle tissues, where HspBP1 is essential for maintaining proper protein folding and function. HspBP1′s ability to bind to Hsp70 and inhibit Hsp70′s activity is vital, as HspBP1 prevents the degradation of immature CFTR forms by the CHIP (C-terminus of Hsp70-interacting protein) pathway, thereby promoting the maturation of CFTR. The proper functioning of CFTR is critical for maintaining ion balance and fluid secretion in epithelial tissues, making HspBP1 an important player in cellular health and disease. Anti-HspBP1 antibody (D-2) is an invaluable tool for researchers studying the intricate mechanisms of protein maturation and the pathophysiology of diseases related to CFTR dysfunction.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HspBP1 Antibody (D-2) | sc-166315 | 200 µg/ml | $322.00 | |||
HspBP1 Antibody (D-2): m-IgG Fc BP-HRP Bundle | sc-537475 | 200 µg Ab; 10 µg BP | $361.00 | |||
HspBP1 Antibody (D-2): m-IgGκ BP-HRP Bundle | sc-534753 | 200 µg Ab; 40 µg BP | $361.00 | |||
HspBP1 Antibody (D-2): m-IgG2b BP-HRP Bundle | sc-549879 | 200 µg Ab; 10 µg BP | $361.00 | |||
HspBP1 (D-2) Neutralizing Peptide | sc-166315 P | 100 µg/0.5 ml | $69.00 |