HHV-6 p41 early antigen Antibody (9A5D12): sc-65447

HHV-6 p41 early antigen Antibody (9A5D12) is a mouse monoclonal IgG2a kappa light chain antibody that detects the p41 early antigen of strain A and B of HHV-6 by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-HHV-6 p41 early antigen antibody (9A5D12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The p41 early antigen plays a crucial role in the viral lifecycle of HHV-6, as p41 early antigen is involved in the early stages of viral replication and is essential for the virus′s ability to establish infection and persist in the host. Understanding the function of p41 early antigen is important because p41 early antigen may provide insights into the mechanisms of viral pathogenesis and the potential for developing targeted therapies or vaccines against HHV-6. The Herpesviridae family, which includes HHV-6, is known for causing a range of diseases in humans, and HHV-6 persistence in various tissues, such as monocytes/macrophages and salivary glands, raises concerns about HHV-6′s role in conditions like multiple sclerosis and other demyelinative diseases. HHV-6 p41 early antigen monoclonal antibody (9A5D12) detection can aid in studying these associations and enhance our understanding of the virus′s impact on human health.

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HHV-6 p41 early antigen Antibody (9A5D12) References:

1. The HHV6 paradox: ubiquitous commensal or insidious pathogen? A two-step in situ PCR approach.  |  Blumberg, BM., et al. 2000. J Clin Virol. 16: 159-78. PMID: 10738136
2. Human herpesvirus 6 (HHV6) infection.  |  Abdel-Haq, NM. and Asmar, BI. 2004. Indian J Pediatr. 71: 89-96. PMID: 14979393
3. Human herpesvirus 6 (HHV6) DNA persistence and reactivation in healthy children.  |  Caserta, MT., et al. 2004. J Pediatr. 145: 478-84. PMID: 15480370
4. Lack of association of polyomavirus and herpesvirus types 6 and 7 in human lymphomas.  |  Hernández-Losa, J., et al. 2005. Cancer. 103: 293-8. PMID: 15593086
5. Fatal pulmonary failure attributable to viral pneumonia with human herpes virus 6 (HHV6) in a young immunocompetent woman.  |  Merk, J., et al. 2005. J Intensive Care Med. 20: 302-6. PMID: 16206417
6. [Drug hypersensitivity syndrome associated with a primary HHV6 infection].  |  Debarbieux, S., et al. 2006. Ann Dermatol Venereol. 133: 145-7. PMID: 16508598
7. Human herpesvirus 6 (HHV6) and chronic fatigue syndrome (CFS).  |  Ablashi, DV., et al. 1991. Can Dis Wkly Rep. 17 Suppl 1E: 33-40. PMID: 1669351
8. Three new human herpesviruses (HHV6, 7, and 8).  |  Levy, JA. 1997. Lancet. 349: 558-63. PMID: 9048803
9. The latency rate of human herpesvirus 6 (HHV6) in positive and negative human immunodeficiency virus (HIV) infection of intravenous drug users (IVDU).  |  Jayavasu, C., et al. 1997. Asian Pac J Allergy Immunol. 15: 29-33. PMID: 9251845

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HHV-6 p41 early antigen Antibody (9A5D12) has 4 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HHV-6 p41 early antigen Antibody (9A5D12) Specifications

Alternate Product Name: HHV-6 p41 early antigen

Product Clone Name: 9A5D12

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids:

Epitope Target: HHV-6 p41 early antigen

Epitope Species: HHV-6

Product Reactivity/Detection: p41 early antigen

Species Reactivity/Detection: strain A, B of HHV-6

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for HHV-6 p41 early antigen Antibody (9A5D12): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin