Molecular structure of Glycolithocholic acid sodium salt, CAS Number: 24404-83-9
Glycolithocholic acid sodium salt (CAS 24404-83-9)
See product citations (3)
Alternate Names:
5β-Cholanic acid-3α-ol N-(carboxymethyl)-amide sodium salt; Sodium Glycolithocholate
Application:
Glycolithocholic acid sodium salt is a bile salt
CAS Number:
24404-83-9
Molecular Weight:
455.61
Molecular Formula:
C26H42NO4•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Glycolithocholic acid sodium salt, a bile acid, plays a role in cholesterol metabolism. It promotes the synthesis of bile acids within the liver, which are subsequently released into the small intestine to aid in the absorption of dietary lipids. Additionally, this compound acts as an agonist for the farnesoid X receptor (FXR), a nuclear receptor responsible for regulating genes associated with bile acid and lipid metabolism.
Glycolithocholic acid sodium salt (CAS 24404-83-9) References
- Rapid quantification of conjugated and unconjugated bile acids and C27 precursors in dried blood spots and small volumes of serum. | Janzen, N., et al. 2010. J Lipid Res. 51: 1591-8. PMID: 20093478
- Estimation of chromatographic lipophilicity of bile acids and their derivatives by reversed-phase thin layer chromatography. | Onişor, C., et al. 2010. J Sep Sci. 33: 3110-8. PMID: 20824659
- Preclinical Evaluation of UDCA-Containing Oral Formulation in Mice for the Treatment of Wet Age-Related Macular Degeneration. | Maharjan, P., et al. 2019. Pharmaceutics. 11: PMID: 31671869
- Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut. | Foley, MH., et al. 2023. Nat Microbiol. 8: 611-628. PMID: 36914755
- Quantitative determination of individual non-sulfated bile acids and sulfated lithocholic acid in serum by mass fragmentography. | Beppu, T., et al. 1981. J Biochem. 89: 1963-73. PMID: 7287668
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glycolithocholic acid sodium salt, 5 mg | sc-396741 | 5 mg | $117.00 |