Eprosartan mesylate (CAS 144143-96-4)

外観 :

Crystalline powder

身体の状態 :

Solid

溶解度 :

Soluble in DMSO (104 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), ethanol (20 mM), DMF (~30 mg/ml), and 1: 1 solution of DMSO: PBS (pH 7.2) (~0.5 mg/ml).

保存方法 :

Store at room temperature

融点 :

>246° C

沸騰点 :

660.6° C at 760 mmHg

屈折率 :

n²⁰_D 1.63 (Predicted)

IC50 :

AT2: IC₅₀ = 1 nM (rat); AT1: IC₅₀ = 1.5 nM (rat mesenteric artery); AT1: IC₅₀ = 1.7 nM (human liver membrane); AT1: IC₅₀ = 3.9 nM (human adrenal cortical membrne); AT1: IC₅₀ = 9.2 nM (rat adrenal cortical membrane)

WGKドイツ :

3

RTECS :

XN0282400

PubChem CID :

Merck 索引 :

14: 3635

MDL番号 :

MFCD08141807

Beilstein レジストリ :

9889741

SMILES :

CCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)/C=C(\\CC3=CC=CS3)/C(=O)O.CS(=O)(=O)O