Date published: 2025-9-12

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(E)-Guggulsterone (CAS 39025-24-6)

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別名:
(17E)-Pregna-4,17(20)-diene-3,16-dione
CAS 番号:
39025-24-6
分子量:
312.45
分子式:
C21H28O2
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* Refer to Certificate of Analysis for lot specific data.

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(E)-Guggulsterone (CAS 39025-24-6) 参考文献

1 Makishima, M., Okamoto, A.Y., Repa, J.J., et al. Identification of a nuclear receptor for bile acids. Science 284 1362-1365 (1999). 2 Barbier, O., Torra, I.P., Sirvent, A., et al. FXR induces the UGT2B4 enzyme in hepatocytes: A potential mechanism of negative feedback control of FXR activity. Gastroenterology 124 1926-1940 (2003). 3 Tan, K.P., Yang, M., Ito, S. Activation of nuclear factor (erythroid-2 like) factor 2 by toxic bile acids provokes adaptive defense responses to enhance cell survival at the emergence of oxidative stress. Mol Pharmacol 72(5) 1380-1390 (2007). 4 Urizar, N.L., Liverman, A.B., Dodds, D.T., et al. A natural product that lowers cholesterol as an anatagonist ligand for FXR. Science 296 1703-1706 (2002). 5 Cui, J., Huang, L., Zhao, A., et al. Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump. The Journal of Biological Chemistry 278(12) 10214-10220 (2003). 6 Wu, J., Xia, C., Meier, J., et al. The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor. Mol Endocrinol 16(7) 1590-1597 (2002).

注文情報

製品名カタログ #単位価格数量お気に入り

(E)-Guggulsterone, 5 mg

sc-294461
5 mg
$510.00

(E)-Guggulsterone, 10 mg

sc-294461A
10 mg
$902.00