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Clathrin HC Antibody (4A8) is a mouse monoclonal IgG1 antibody that detects Clathrin HC in soybean by western blotting (WB) and immunofluorescence (IF). Clathrin HC is a crucial component of the clathrin coat, which plays a vital role in receptor-mediated endocytosis, a process essential for cellular uptake of nutrients and signaling molecules. Clathrin HC is primarily located in the cytosol, where Clathrin HC assembles into a triskelion structure composed of three heavy chains and three light chains. This structural arrangement is critical for the formation of clathrin-coated vesicles, which facilitate the invagination of the plasma membrane and the subsequent internalization of receptor-ligand complexes. The ability of Clathrin HC to interact with various proteins, including adaptors and receptors, underscores Clathrin HC′s importance in maintaining cellular homeostasis and regulating intracellular trafficking. Anti-Clathrin HC antibody (4A8) is an invaluable tool for researchers studying endocytic pathways and the dynamics of vesicle formation in plant systems.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Clathrin Heavy Chain/CLTC Antibody (4A8) | sc-57684 | 200 µg/ml | $322.00 | |||
Clathrin Heavy Chain/CLTC Antibody (4A8): m-IgG Fc BP-HRP Bundle | sc-537141 | 200 µg Ab; 10 µg BP | $361.00 | |||
Clathrin Heavy Chain/CLTC Antibody (4A8): m-IgGκ BP-HRP Bundle | sc-534334 | 200 µg Ab; 40 µg BP | $361.00 | |||
Clathrin Heavy Chain/CLTC Antibody (4A8): m-IgG1 BP-HRP Bundle | sc-545031 | 200 µg Ab; 20 µg BP | $361.00 |