Molecular structure of CGS 15943, CAS Number: 104615-18-1
CGS 15943 (CAS 104615-18-1)
See product citations (4)
Alternate Names:
9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
Application:
CGS 15943 is a potent Adenosine A Receptor antagonist
CAS Number:
104615-18-1
Purity:
≥99%
Molecular Weight:
285.69
Molecular Formula:
C13H8ClN5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
CGS 15943 is a potent, non-selective Adenosine A Receptor antagonist. CGS 15943 is a synthetic compound derived from the heterocyclic class of compounds. It is orally active in vivo. It has been studied for its potential to act as an antioxidant in in vitro studies.
CGS 15943 (CAS 104615-18-1) References
- Discriminative effects of CGS 15943, a competitive adenosine receptor antagonist, have a dopamine component in monkeys. | Holtzman, SG. 1999. Eur J Pharmacol. 376: 7-15. PMID: 10440083
- Adenosine receptors and their ligands. | Klotz, KN. 2000. Naunyn Schmiedebergs Arch Pharmacol. 362: 382-91. PMID: 11111832
- Selective adenosine A2A receptor antagonists. | Ongini, E., et al. 2001. Farmaco. 56: 87-90. PMID: 11347973
- CGS 15943, a nonxanthine adenosine receptor antagonist: effects on locomotor activity of nontolerant and caffeine-tolerant rats. | Holtzman, SG. 1991. Life Sci. 49: 1563-70. PMID: 1943461
- Influence of CGS 15943 A (a nonxanthine adenosine antagonist) on the protection offered by a variety of antiepileptic drugs against maximal electroshock-induced seizures in mice. | Czuczwar, SJ., et al. 1991. J Neural Transm Gen Sect. 86: 127-34. PMID: 1953988
- Characterization of the binding of a novel nonxanthine adenosine antagonist radioligand, [3H]CGS 15943, to multiple affinity states of the adenosine A1 receptor in the rat cortex. | Jarvis, MF., et al. 1991. Mol Pharmacol. 39: 49-54. PMID: 1987452
- Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway. | Edling, CE., et al. 2014. Cancer Biol Ther. 15: 524-32. PMID: 24521981
- Biochemical characterization of the triazoloquinazoline, CGS 15943, a novel, non-xanthine adenosine antagonist. | Williams, M., et al. 1987. J Pharmacol Exp Ther. 241: 415-20. PMID: 2883298
- Pharmacological characterization of CGS 15943A: a novel nonxanthine adenosine antagonist. | Ghai, G., et al. 1987. J Pharmacol Exp Ther. 242: 784-90. PMID: 3656113
- CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the Mongolian gerbil. | Gao, Y. and Phillis, JW. 1994. Life Sci. 55: PL61-5. PMID: 8007757
- Effects of CGS 15943, a nonxanthine adenosine antagonist, on behavior in the squirrel monkey. | Howell, LL. and Byrd, LD. 1993. J Pharmacol Exp Ther. 267: 432-9. PMID: 8229772
- Discriminative effects of CGS 15943, a competitive adenosine receptor antagonist, in monkeys: comparison to methylxanthines. | Holtzman, SG. 1996. J Pharmacol Exp Ther. 277: 739-46. PMID: 8627553
- Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors. | Ongini, E., et al. 1999. Naunyn Schmiedebergs Arch Pharmacol. 359: 7-10. PMID: 9933143
Inhibitor of:
Adenosine A Receptor, Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R, and Adenosine A3-R.Activator of:
Rab 1A.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CGS 15943, 10 mg | sc-203544 | 10 mg | $89.00 | |||
CGS 15943, 50 mg | sc-203544A | 50 mg | $406.00 |