(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid (CAS 100828-16-8)

身体の状態 :

Solid

溶解度 :

Soluble in 1 N NaOH (at 100 mM), and water (to 100 mM). Insoluble in ethanol.

保存方法 :

Desiccate at room temperature

沸騰点 :

546.7° C at 760 mmHg

密度 :

1.41 g/cm³

屈折率 :

n²⁰_D 1.53

IC50 :

Glutamate NMDA receptor: IC₅₀ = 28 nM (rat); Glutamate [NMDA] receptor subunit epsilon 1: IC₅₀ = 72 nM (mouse); Glutamate [NMDA] receptor subunit 3A: IC₅₀ = 72 nM (mouse); Glutamate [NMDA] receptor subunit epsilon 2: IC₅₀ = 72 nM (mouse); Glutamate [NMDA] receptor subunit epsilon 3: IC₅₀ = 72 nM (mouse)

Ki データ :

Glutamate [NMDA] receptor subunit epsilon 3: K_i= 131 nM (rat); Glutamate [NMDA] receptor subunit epsilon 1: K_i= 131 nM (rat); Glutamate [NMDA] receptor subunit epsilon 2: K_i= 131 nM (rat); Glutamate [NMDA] receptor subunit epsilon 4: K_i= 131 nM (rat)

pK値 :

pK_a: 1.89 (Predicted), pK_b: 9.42 (Predicted)

WGKドイツ :

3

PubChem CID :

MDL番号 :

MFCD00055136

SMILES :

C1CN(CC(N1)C(=O)O)CCCP(=O)(O)O