IL-17REL アクチベーター

IL-17REL is a member of the interleukin-17 (IL-17) family of cytokines, which are known for their role in inflammatory processes and host defense against infections. This family includes several members, such as IL-17A through IL-17F, each encoded by different genes and exhibiting distinct but related biological functions. IL-17 cytokines are predominantly produced by a unique subset of T cells known as Th17 cells, although other cell types like γδ T cells and innate immune cells can also produce them under certain conditions.

IL-17REL is the least characterized member of the IL-17 family and shares sequence homology with other IL-17 family cytokines, suggesting it may have similar biological activities. The "REL" suffix denotes its relationship to the other IL-17 family members, but also its distinctiveness, as it is not as extensively studied. Due to the naming conventions of cytokines, the "REL" might imply a relative or a homolog to the better-characterized IL-17 cytokines, particularly IL-17A and IL-17F, which are the most studied and are known to mediate pro-inflammatory responses.While the exact function of IL-17REL is not well-defined, it is presumed to be involved in immune system signaling pathways, contributing to the orchestration of immune responses. Like other IL-17 cytokines, it may play a role in inducing the production of other pro-inflammatory molecules, such as chemokines and cytokines, which recruit and activate other immune cells to the site of infection or inflammation.