IBA2 アクチベーター

IBA2 is a protein encoded by the PLEKHM1P gene in humans. This gene is also known as "IBA2 pseudogene," indicating that it is a non-functional copy of a gene. Pseudogenes arise from the duplication or mutation of existing genes, and they typically do not produce functional proteins due to accumulated mutations or alterations in their sequences.However, the original functional gene related to IBA2, from which the pseudogene is derived, has significance in biological research. IBA2 generally refers to "Ionized calcium-Binding Adapter molecule 2," which is involved in various cellular processes, particularly in the immune and nervous systems.

In its functional form, IBA2 is known to be involved in the modulation of calcium signaling within cells. Calcium ions are crucial secondary messengers in cellular signaling pathways, influencing processes such as neurotransmission, muscle contraction, and immune responses. Proteins like IBA2 that bind to calcium ions play critical roles in regulating these processes.IBA2 has been particularly studied in the context of the nervous system and immune system. In the nervous system, it is involved in neuronal development and function, influencing synaptic plasticity and neurotransmitter release. In the immune system, IBA2 may participate in the regulation of immune cell function, such as in the activation and response of macrophages and other immune cells.The study of IBA2, therefore, contributes to our understanding of calcium-dependent signaling in various physiological processes and the implications of these processes in health and disease.