ATPIF1 Activators
ATPIF1 Activators are a class of chemical compounds that can enhance the functional activity of ATPIF1. ATPIF1, or ATPase Inhibitory Factor 1, is a protein that modulates ATP synthase within the mitochondria. The activity of ATPIF1 is determined by the ATP:ADP ratio within the cell. Chemicals like A-769662, AICAR, Metformin, Berberine, Capsaicin, Phenformin, Salicylate, and Troglitazone can enhance the activity of ATPIF1 by activating AMP-activated protein kinase (AMPK) or Peroxisome proliferator-activated receptor gamma (PPARγ), leading to an enhancement of mitochondrial biogenesis and increased ATP production.
Other compounds such as 2-Deoxy-D-glucose and Dorsomorphin enhance the activity of ATPIF1 by increasing the cell's reliance on mitochondrial ATP production. 2-Deoxy-D-glucose achieves this by inhibiting glycolysis, a process that generates ATP outside the mitochondria. Dorsomorphin does this by inhibiting AMPK, causing a shift towards ATP synthase-based ATP production. Resveratrol and Quercetin enhance the activity of ATPIF1 by activating SIRT1, a protein that modulates energy metabolism and increases ATP production. These compounds, by virtue of their influence on these pathways, can enhance the functional activity of ATPIF1.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $184.00 $741.00 $1076.00 $3417.00 $5304.00 | 23 | |
A-769662 activates the AMPK pathway. The activation of AMPK leads to elevated ATP production. As ATPIF1 acts as a modulator of ATP synthase, increased ATP production enhances the functional activity of ATPIF1. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
2-Deoxy-D-glucose inhibits glycolysis. This inhibition pushes the cell to rely more on mitochondrial ATP production, leading to increased ATP synthase activity and indirectly enhancing the functional activity of ATPIF1. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR activates AMPK, leading to increased ATP production. The increased ATP production in turn enhances the functional activity of ATPIF1 by increasing the ATP:ADP ratio. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
Metformin activates AMPK, leading to the enhancement of mitochondrial biogenesis and ATP production. The rise in ATP production enhances the functional activity of ATPIF1. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates SIRT1, which influences energy metabolism and increases ATP production. The elevated ATP production indirectly enhances the functional activity of ATPIF1. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine activates AMPK, leading to increased ATP production. The elevated ATP production indirectly enhances the functional activity of ATPIF1. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin activates the TRPV1 receptor, leading to a calcium influx and activation of CaMKKβ, which can subsequently activate AMPK. The AMPK activation leads to increased ATP production, indirectly enhancing the functional activity of ATPIF1. | ||||||
Phenformin Hydrochloride | 834-28-6 | sc-219590 | 10 g | $119.00 | 4 | |
Phenformin activates AMPK, leading to enhanced mitochondrial biogenesis and ATP production. The increased ATP production indirectly enhances the functional activity of ATPIF1. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $96.00 $355.00 | 69 | |
Dorsomorphin inhibits AMPK, leading to an increased reliance on ATP synthase-based ATP production. This action indirectly enhances the functional activity of ATPIF1. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $47.00 $94.00 $119.00 | 3 | |
Salicylate activates AMPK, leading to enhanced mitochondrial biogenesis and ATP production. The increased ATP production indirectly enhances the functional activity of ATPIF1. | ||||||