ZNF181 Antibody (16-Z): sc-101076
- ZNF181 Antibody (16-Z) is a mouse monoclonal IgG2a κ ZNF181 antibody provided at 50 µg/0.5 ml
- raised against recombinant ZNF181 of human origin
- recommended for detection of ZNF181 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ZNF181 Antibody (16-Z). This work is in progress.
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ZNF181 Antibody (16-Z) is a mouse monoclonal IgG2a kappa light chain antibody that detects ZNF181 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-ZNF181 antibody (16-Z) is available as a non-conjugated format. ZNF181, also known as HHZ181, is a 571 amino acid protein characterized by its unique structure, which includes one KRAB domain and eleven C2H2-type zinc fingers. This structural composition enables ZNF181 to bind to specific DNA sequences, thereby playing a significant role in transcriptional regulation. The presence of the KRAB domain interacts with the KAP1 protein, facilitating the recruitment of histone-modifying enzymes that can alter chromatin structure and influence gene expression. ZNF181 is localized to the nucleus, where ZNF181 participates in various cellular processes, including the regulation of gene expression in response to developmental and environmental signals. Two isoforms of ZNF181 arise from alternative splicing, which may contribute to functional diversity in different cellular contexts.
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ZNF181 Antibody (16-Z) References:
- The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor. | Sun, Y., et al. 2003. IUBMB Life. 55: 127-31. PMID: 12822888
- Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome. | Englbrecht, CC., et al. 2004. BMC Genomics. 5: 39. PMID: 15236668
- A novel subfamily of zinc finger genes involved in embryonic development. | Nakamura, M., et al. 2004. J Cell Biochem. 93: 887-95. PMID: 15449319
- Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs. | O'Geen, H., et al. 2007. PLoS Genet. 3: e89. PMID: 17542650
- Identification of a locus of zinc finger genes in human chromosome 19q13.1-q13.3 region by fluorescence in situ hybridization. | Wang, R., et al. 1996. Somat Cell Mol Genet. 22: 245-8. PMID: 8914611
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF181 Antibody (16-Z) | sc-101076 | 50 µg/0.5 ml | $322.00 |