VZV NC Antibody (0371): sc-58082
- VZV NC Antibody (0371) is a mouse monoclonal IgG1 VZV NC antibody provided at 100 µg/ml
- raised against VZV NC
- recommended for detection of VZV nucleocapsid of Varicella Zoster Virus origin by IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for VZV NC Antibody (0371). This work is in progress.
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VZV NC Antibody (0371) is a mouse monoclonal IgG1 antibody that detects the VZV NC protein of Varicella Zoster Virus origin by immunofluorescence (IF). Anti-VZV NC antibody (0371) is available as the non-conjugated format. Varicella-zoster virus (VZV) is a prevalent human alphaherpesvirus responsible for two significant diseases: childhood chickenpox (varicella) and shingles (zoster). The VZV NC protein, encoded by VZV gene 40, plays a crucial role in the virus′s life cycle by forming the nucleocapsid, which is essential for protecting the viral genome and facilitating delivery into host cells. VZV NC protein′s structure comprises an icosahedral arrangement that enhances viral particle stability, allowing for efficient infection and replication within the host. VZV NC protein is instrumental in eliciting a humoral immune response, which is critical for the host′s defense against the virus. Understanding VZV NC protein function and structure is important for developing therapeutic strategies and vaccines aimed at controlling VZV infections.
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VZV NC Antibody (0371) References:
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- Identification of small molecule compounds that selectively inhibit varicella-zoster virus replication. | Visalli, RJ., et al. 2003. J Virol. 77: 2349-58. PMID: 12551972
- Antigenic cross-reaction between a varicella-zoster virus nucleocapsid protein encoded by gene 40 and a herpes simplex virus nucleocapsid protein. | Vafai, A., et al. 1990. Virus Res. 15: 163-74. PMID: 2157317
- Perinatal cytomegalovirus and varicella zoster virus infections: epidemiology, prevention, and treatment. | Bialas, KM., et al. 2015. Clin Perinatol. 42: 61-75, viii. PMID: 25677997
- Errant processing and structural alterations of genomes present in a varicella-zoster virus vaccine. | Vlazny, DA. and Hyman, RW. 1985. J Virol. 56: 92-101. PMID: 2993670
- Targeted RNA Sequencing of VZV-Infected Brain Vascular Adventitial Fibroblasts Indicates That Amyloid May Be Involved in VZV Vasculopathy. | Bubak, AN., et al. 2022. Neurol Neuroimmunol Neuroinflamm. 9: PMID: 34759019
- Tegument protein UL21 of alpha-herpesvirus inhibits the innate immunity by triggering CGAS degradation through TOLLIP-mediated selective autophagy. | Ma, Z., et al. 2023. Autophagy. 19: 1512-1532. PMID: 36343628
- Egress of varicella-zoster virus from the melanoma cell: a tropism for the melanocyte. | Harson, R. and Grose, C. 1995. J Virol. 69: 4994-5010. PMID: 7609070
- Varicella-zoster virus. | Arvin, AM. 1996. Clin Microbiol Rev. 9: 361-81. PMID: 8809466
- Varicella-zoster virus. The virus. | Cohen, JI. 1996. Infect Dis Clin North Am. 10: 457-68. PMID: 8856347
- Molecular biology of varicella-zoster virus. A review prepared for the UK Advisory Group on Chickenpox. | Harper, DR., et al. 1998. J Infect. 36 Suppl 1: 1-10. PMID: 9514102
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VZV NC Antibody (0371) | sc-58082 | 100 µg/ml | $322.00 |