Timeless Antibody (G-4): sc-393146

Timeless Antibody (G-4) is a mouse monoclonal IgG2a antibody that detects Timeless in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Timeless (G-4) antibody recognizes a crucial component of the circadian clock, playing a significant role in regulating the timing of various biological processes, including sleep-wake cycles and hormonal rhythms. Located primarily in the nucleus, anti-Timeless antibody (G-4) detects proteins that interact with period proteins, specifically Per1 and Per2, to modulate their activity and stability, which is essential for maintaining the rhythmic expression of clock genes. This interaction is vital because disruptions in the circadian rhythm can lead to various health issues, including sleep disorders and metabolic syndromes. Timeless monoclonal antibody (G-4) provides researchers with a powerful tool to study the dynamics of circadian regulation and its implications in both physiological and pathological states, enabling a deeper understanding of how these biological timepieces influence overall health and behavior.

The preferred Timeless antibody is Timeless Antibody (A-3): sc-393122.