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TFIID Antibody (ITBP20) is a mouse monoclonal IgG1 antibody that detects TFIID in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). TFIID plays a crucial role in the initiation of transcription by RNA polymerase II, serving as a key component of the pre-initiation complex that assembles at the core promoter region of protein-coding genes. This complex is essential for the accurate and efficient transcription of genes, as TFIID binds to the TATA box, a conserved DNA sequence located approximately 25-30 base pairs upstream of the transcription start site. The TATA-binding subunit of TFIID, known as TBP, contains a highly-conserved C-terminal domain of 180 amino acids that is critical for its function, as TBP facilitates the recruitment of other transcription factors necessary for the formation of the transcription machinery. The proper functioning of TFIID is vital for gene expression regulation, and any dysregulation can lead to various diseases, including cancer. Anti-TFIID antibody (ITBP20) is an invaluable tool for researchers studying transcriptional regulation and its implications in cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TFIID/TATA Binding Protein/TBP Antibody (ITBP20) | sc-56796 | 200 µg/ml | $322.00 | |||
TFIID/TATA Binding Protein/TBP Antibody (ITBP20): m-IgG Fc BP-HRP Bundle | sc-537122 | 200 µg Ab; 10 µg BP | $361.00 | |||
TFIID/TATA Binding Protein/TBP Antibody (ITBP20): m-IgGκ BP-HRP Bundle | sc-534314 | 200 µg Ab; 40 µg BP | $361.00 | |||
TFIID/TATA Binding Protein/TBP Antibody (ITBP20): m-IgG1 BP-HRP Bundle | sc-545017 | 200 µg Ab; 20 µg BP | $361.00 |