TEX10 Antibody (B-9): sc-398384
- TEX10 Antibody (B-9) is a mouse monoclonal IgG1 κ TEX10 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 23-322 mapping near the N-terminus of TEX10 of human origin
- TEX10 Antibody (B-9) is recommended for detection of TEX10 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TEX10 Antibody (B-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TEX10 Antibody (B-9) for WB applications. These reagents are now offered in bundles with TEX10 Antibody (B-9) (see ordering information below).
TEX10 Antibody (B-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects TEX10 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TEX10 (B-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TEX10 protein, also known as testis expressed 10, L18, or Nbla10363, is a 929 amino acid multi-pass membrane protein that primarily localizes to the nucleus, where TEX10 plays a crucial role in gene regulation and cellular processes. The presence of one HEAT repeat in TEX10′s structure is significant as this suggests a potential for protein-protein interactions, which are essential for TEX10′s function in modulating transcriptional activity. The gene encoding TEX10 is located on human chromosome 9, a region that is notable not only for its size—comprising 4% of the human genome and encoding nearly 900 genes—but also for its association with various genetic disorders, including hereditary hemorrhagic telangiectasia and familial dysautonomia. Understanding TEX10′s function and interactions is vital, as this may contribute to the development of therapeutic strategies targeting diseases linked to chromosomal abnormalities and gene expression dysregulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TEX10 Antibody (B-9) References:
- DNA sequence and analysis of human chromosome 9. | Humphray, SJ., et al. 2004. Nature. 429: 369-74. PMID: 15164053
- BCR-ABL activates STAT3 via JAK and MEK pathways in human cells. | Coppo, P., et al. 2006. Br J Haematol. 134: 171-9. PMID: 16846476
- BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility. | Zheng, X., et al. 2006. BMC Cancer. 6: 262. PMID: 17090304
- Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia. | Fernandez-L, A., et al. 2007. Hum Mol Genet. 16: 1515-33. PMID: 17420163
- Phenotypic and cytogenetic spectrum of 9p trisomy. | Temtamy, SA., et al. 2007. Genet Couns. 18: 29-48. PMID: 17515299
- Potential role of tubulin acetylation and microtubule-based protein trafficking in familial dysautonomia. | Gardiner, J., et al. 2007. Traffic. 8: 1145-9. PMID: 17605759
- Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease). | Cottin, V., et al. 2007. Respiration. 74: 361-78. PMID: 17641482
- A humanized IKBKAP transgenic mouse models a tissue-specific human splicing defect. | Hims, MM., et al. 2007. Genomics. 90: 389-96. PMID: 17644305
- Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia. | Burmeister, T., et al. 2007. Haematologica. 92: 1699-702. PMID: 18055996
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TEX10 Antibody (B-9) | sc-398384 | 200 µg/ml | $322.00 | |||
TEX10 Antibody (B-9): m-IgG Fc BP-HRP Bundle | sc-527767 | 200 µg Ab; 10 µg BP | $361.00 | |||
TEX10 Antibody (B-9): m-IgG1 BP-HRP Bundle | sc-533140 | 200 µg Ab; 20 µg BP | $361.00 | |||
TEX10 Antibody (B-9) AC | sc-398384 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TEX10 Antibody (B-9) HRP | sc-398384 HRP | 200 µg/ml | $322.00 | |||
TEX10 Antibody (B-9) FITC | sc-398384 FITC | 200 µg/ml | $336.00 | |||
TEX10 Antibody (B-9) PE | sc-398384 PE | 200 µg/ml | $349.00 | |||
TEX10 Antibody (B-9) Alexa Fluor® 488 | sc-398384 AF488 | 200 µg/ml | $364.00 | |||
TEX10 Antibody (B-9) Alexa Fluor® 546 | sc-398384 AF546 | 200 µg/ml | $364.00 | |||
TEX10 Antibody (B-9) Alexa Fluor® 594 | sc-398384 AF594 | 200 µg/ml | $364.00 | |||
TEX10 Antibody (B-9) Alexa Fluor® 647 | sc-398384 AF647 | 200 µg/ml | $364.00 | |||
TEX10 Antibody (B-9) Alexa Fluor® 680 | sc-398384 AF680 | 200 µg/ml | $364.00 | |||
TEX10 Antibody (B-9) Alexa Fluor® 790 | sc-398384 AF790 | 200 µg/ml | $364.00 |