Anti-RFC1 Antibody B-5 è un monoclonale di topo IgG2a κ RFC1 antibody, citato in 2 pubblicazioni, fornito in 200 µg/ml
generato contro gli amminoacidi 848-1147 mappati al C-terminus di RFC1 di origine human
RFC1 Antibody (B-5) é raccomandato per il rilevamento di RFC1 di origine human in WB, IP, IF e ELISA
RFC1 Antibody (B-5) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di RFC1 (B-5): sc-271656.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for RFC1 Antibody (B-5) for WB applications. These reagents are now offered in bundles with RFC1 Antibody (B-5) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
RFC1 Antibody (B-5) is a high quality monoclonal RFC1 antibody (also designated RFC1 antibody) suitable for the detection of the RFC1 protein of human origin. RFC1 Antibody (B-5) is available as both the non-conjugated anti-RFC1 antibody form, as well as multiple conjugated forms of anti-RFC1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Replication factor C (RFC) is an essential DNA polymerase accessory protein that is required for numerous aspects of DNA metabolism, including DNA replication, DNA repair and telomere metabolism. RFC is a heteropentameric complex that recognizes a primer on a template DNA, binds to a primer terminus and loads proliferating cell nuclear antigen (PCNA) onto DNA at primer-template junctions in an ATP-dependent reaction. All five of the RFC subunits share a set of related sequences (RFC boxes) that include nucleotide-binding consensus sequences. Four of the five RFC genes (including RFC1, RFC2, RFC3 and RFC4) have consensus ATP-binding motifs. The small RFC proteins, RFC2, RFC3, RFC4 and RFC5, interact with Rad24, whereas the RFC1 subunit does not. RFC1 is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during FAS-mediated apoptosis. In addition, phosphorylation of the PCNA binding domain of RFC1 by Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibits DNA synthesis. The human RFC1 gene maps to chromosome 4p14 and encodes the RFC1 subunit.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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