RDH11 Antibody (EE-12): sc-100588

RDH11 Antibody (EE-12) is a mouse monoclonal IgG1 antibody that detects RDH11 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). RDH11 is a crucial enzyme belonging to the short chain retinol dehydrogenase/reductase family, functioning primarily as an oxidoreductive catalyst for retinoids. RDH11 plays a vital role in the retinoid cycle, particularly in the retinal pigment epithelium, where RDH11 catalyzes the conversion of 11-cis-retinol to 11-cis retinal, a key step in the regeneration of visual pigments necessary for proper vision. The efficient functioning of RDH11 is essential for maintaining the balance of retinoids in the eye, which is critical for phototransduction and overall visual health. Although RDH11 is expressed in various tissues, including the liver and prostate, RDH11′s specific activity in the retina underscores its importance in ocular physiology. Notably, there are currently no known diseases associated with mutations in the gene encoding RDH11, highlighting RDH11′s potential as a stable target for research and therapeutic applications. Anti-RDH11 antibody (EE-12) is an invaluable tool for researchers investigating the dynamics of retinoid metabolism and its implications in vision-related studies.

The preferred RDH11 antibody is RDH11 Antibody (F-1): sc-514370.