RAIDD Antibody (B-1): sc-374447

RAIDD Antibody (B-1) is a mouse monoclonal IgG2b antibody that detects RAIDD in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RAIDD, or RIP-associated ICH-1/Ced-3 homologous protein with a death domain, plays a crucial role in the apoptotic signaling pathway by acting as a mediator that links the tumor necrosis factor receptors (TNFRs) to the activation of caspases, which are essential for the execution of apoptosis. RAIDD contains a death domain that allows interaction with other death domain-containing proteins, such as receptor interacting protein (RIP) and members of the caspase family, thereby facilitating the transduction of apoptotic signals. This interaction is vital for maintaining cellular homeostasis and regulating programmed cell death, which is important in various physiological processes and in the prevention of diseases such as cancer. Anti-RAIDD antibody (B-1) is an invaluable tool for researchers studying apoptosis and its implications in human health and disease, providing insights into the molecular mechanisms that govern cell death and survival.

The preferred RAIDD antibody is RAIDD Antibody (G-7): sc-377080.