Date published: 2026-4-24

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Potassium 1-trifluoroboratomethylpyrrolidine (CAS 888711-53-3)

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CAS Number:
888711-53-3
Molecular Weight:
191.04
Molecular Formula:
C5H10BF3KN
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Potassium 1-trifluoroboratomethylpyrrolidine (KTFMB) is a boron-containing compound that finds utility as both a reagent and a catalyst in diverse synthetic and chemical processes. The scientific research applications of Potassium 1-trifluoroboratomethylpyrrolidine encompass the synthesis of polymers and other materials. Additionally, its catalytic potential has been harnessed in various chemical reactions, such as the Stetter reaction, Wittig reaction, and Ugi reaction. Potassium 1-trifluoroboratomethylpyrrolidine has also been instrumental in the synthesis of organometallic compounds, like palladium complexes, and the creation of complex organic molecules, including peptides and proteins. Potassium 1-trifluoroboratomethylpyrrolidine acts as a Lewis acid, capable of accepting an electron pair from another molecule. This unique property allows the boron atom of Potassium 1-trifluoroboratomethylpyrrolidine to attract the electron pair of a substrate molecule, leading to the formation of a new covalent bond between the substrate and the boron atom. This covalent bond formation underpins the catalytic activity of Potassium 1-trifluoroboratomethylpyrrolidine, making it useful in various chemical transformations.


Potassium 1-trifluoroboratomethylpyrrolidine (CAS 888711-53-3) References

  1. Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods.  |  Sarkar, D., et al. 2020. J Med Chem. 63: 8325-8337. PMID: 32673492

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Potassium 1-trifluoroboratomethylpyrrolidine, 1 g

sc-272051
1 g
$180.00

Potassium 1-trifluoroboratomethylpyrrolidine, 5 g

sc-272051A
5 g
$667.00