p-p70 S6 kinase alpha Antibody E-5 è un monoclonale di topo IgG1 κ, citato in 6 pubblicazioni, fornito in 200 µg/ml
p-p70 S6 kinase alpha Antibody (E-5) é raccomandato per il rilevamento di Thr 421 and Ser 424 dually phosphorylated p70 S6 kinase α di origine mouse, rat, human e in WB, IP, IF and ELISA; anche reattivo con ulteriori specie, incluse e equine, canine, bovine, porcine and avian
p-p70 S6 kinase alpha Antibody (E-5) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di p-p70 S6 kinase α (E-5): sc-377529.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p-p70 S6 kinase α Antibody (E-5) for WB applications. These reagents are now offered in bundles with p-p70 S6 kinase α Antibody (E-5) (see ordering information below).
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
In studies to elucidate key regulatory pathways in signal transduction, several protein serine/threonine (Ser/Thr) kinases have been identified. Included among such kinases are two distinct families of 40S ribosomal protein S6 Ser/Thr kinases present in somatic animal cells, designated p70 S6 kinase and p90 Rsk kinase. p90 Rsk kinase is maximally activated within minutes of addition of growth factors or phorbol ester to cultured cells followed by activation of p70 S6 kinase. Both enzymes are regulated by serine/threonine phosphorylation, suggesting that specific kinases may exist upstream in the signaling pathway that regulate these kinases. In fact, evidence suggests that one such family of activating enzymes includes the members of the ERK MAP kinase family. The ERK MAP kinases are, in turn, regulated by phosphorylation at threonine and tyrosine residues by a protein kinase designated MEK.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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