p-Cofilin 1 Antibody (F-11): sc-365882
- p-Cofilin 1 Antibody (F-11) is a mouse monoclonal IgG2b κ, cited in 4 publications, provided at 200 µg/ml
- Anti-p-Cofilin 1 Antibody (F-11) is recommended for detection of Ser 3 phosphorylated Cofilin 1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-p-Cofilin 1 Antibody (F-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for p-Cofilin 1 Antibody (F-11) for WB and IHC(P) applications. These reagents are now offered in bundles with p-Cofilin 1 Antibody (F-11) (see ordering information below).
p-Cofilin 1 Antibody (F-11) is a mouse monoclonal IgG2b kappa light chain antibody that detects Ser 3 phosphorylated Cofilin 1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). p-Cofilin 1 (F-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Cofilin 1 plays a crucial role in actin dynamics by regulating the turnover and organization of the actin cytoskeleton, which is essential for various cellular processes such as motility, division, and shape maintenance. The phosphorylation of Cofilin 1 at Serine 3, mediated by LIM-kinase 1 (LIMK-1), inhibits actin-depolymerizing activity, thereby stabilizing actin filaments and promoting the formation of a robust cytoskeletal network. This regulatory mechanism is vital for maintaining cellular architecture and responding to signaling pathways that dictate cytoskeletal rearrangements. Anti-p-Cofilin 1 antibody (F-11) enables researchers to gain insights into the intricate balance of actin dynamics and its implications in cellular functions and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-Cofilin 1 Antibody (F-11) | sc-365882 | 200 µg/ml | $322.00 | |||
p-Cofilin 1 Antibody (F-11): m-IgG Fc BP-HRP Bundle | sc-525905 | 200 µg Ab; 10 µg BP | $361.00 | |||
p-Cofilin 1 Antibody (F-11): m-IgG2b BP-HRP Bundle | sc-549646 | 200 µg Ab; 10 µg BP | $361.00 | |||
p-Cofilin 1 Antibody (F-11) AC | sc-365882 AC | 500 µg/ml, 25% agarose | $424.00 | |||
p-Cofilin 1 Antibody (F-11) HRP | sc-365882 HRP | 200 µg/ml | $322.00 | |||
p-Cofilin 1 Antibody (F-11) FITC | sc-365882 FITC | 200 µg/ml | $336.00 | |||
p-Cofilin 1 Antibody (F-11) PE | sc-365882 PE | 200 µg/ml | $349.00 | |||
p-Cofilin 1 Antibody (F-11) Alexa Fluor® 488 | sc-365882 AF488 | 200 µg/ml | $364.00 | |||
p-Cofilin 1 Antibody (F-11) Alexa Fluor® 546 | sc-365882 AF546 | 200 µg/ml | $364.00 | |||
p-Cofilin 1 Antibody (F-11) Alexa Fluor® 594 | sc-365882 AF594 | 200 µg/ml | $364.00 | |||
p-Cofilin 1 Antibody (F-11) Alexa Fluor® 647 | sc-365882 AF647 | 200 µg/ml | $364.00 | |||
p-Cofilin 1 Antibody (F-11) Alexa Fluor® 680 | sc-365882 AF680 | 200 µg/ml | $364.00 | |||
p-Cofilin 1 Antibody (F-11) Alexa Fluor® 790 | sc-365882 AF790 | 200 µg/ml | $364.00 | |||
p-Cofilin 1 (F-11) Neutralizing Peptide | sc-365882 P | 100 µg/0.5 ml | $69.00 |