NAB1 Antibody (2607C2a): sc-81565
- NAB1 Antibody (2607C2a) is a mouse monoclonal IgG1, cited in 2 publications, provided at 100 µg/ml
- raised against a recombinant protein corresponding to a region near the C-terminus of NAB1 of human origin
- recommended for detection of NAB1 of mouse, rat and human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NAB1 Antibody (2607C2a). This work is in progress.
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NAB1 Antibody (2607C2a) is a mouse monoclonal IgG1 antibody that detects NAB1 in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Anti-NAB1 antibody (2607C2a) is crucial for understanding NAB1′s role in transcriptional regulation, particularly as a corepressor of the transcription factor Egr1/NGFI-A. NAB1 is primarily localized in the nucleus, where NAB1 interacts with DNA-bound transcription factors to modulate gene expression. Nuclear localization of NAB1 allows direct access to transcriptional machinery, influencing critical cellular processes such as cell division, differentiation, and apoptosis. NAB1 contains essential domains, including the NAB-conserved domain 1 (NCB1), which is necessary for binding to NGFI-A, and the carboxy-terminal NCD2, which is responsible for repressive function. Understanding NAB1 dynamics and interactions provides insights into regulatory networks governing cellular behavior and implications of dysregulation in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NAB1 Antibody (2607C2a) | sc-81565 | 100 µg/ml | $339.00 |