Molecular structure of Mycophenolate mofetil, CAS Number: 128794-94-5
Mycophenolate mofetil (CAS 128794-94-5)
See product citations (1)
Application:
Mycophenolate mofetil is a compound that suppresses T-lymphocytic and antibody responses
CAS Number:
128794-94-5
Purity:
≥99%
Molecular Weight:
433.5
Molecular Formula:
C23H31NO7
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Mycophenolate mofetil may act to suppress the T-lymphocytic and antibody responses. Studies indicate that the function of mycophenolate mofetil is compromised by proton pump inhibitors and it displays antiproliferative properties without cytotoxic effects. Mycophenolate mofetil has been used in multiple kidney studies. Mycophenolate mofetil is an inhibitor of IMPDH.
Mycophenolate mofetil (CAS 128794-94-5) References
- Mycophenolate mofetil and its mechanisms of action. | Allison, AC. and Eugui, EM. 2000. Immunopharmacology. 47: 85-118. PMID: 10878285
- Mycophenolate mofetil: selective T cell inhibition. | McMurray, RW. and Harisdangkul, V. 2002. Am J Med Sci. 323: 194-6. PMID: 12003374
- Enteric-coated mycophenolate sodium. | Gabardi, S., et al. 2003. Ann Pharmacother. 37: 1685-93. PMID: 14565799
- Mycophenolate mofetil inhibits human Tenon fibroblast proliferation by guanosine depletion. | Heinz, C., et al. 2003. Br J Ophthalmol. 87: 1397-8. PMID: 14609842
- Effects of mycophenolate mofetil on cardiac allograft survival and cardiac allograft vasculopathy in miniature swine. | Schwarze, ML., et al. 2005. Ann Thorac Surg. 80: 1787-93. PMID: 16242456
- Mycophenolate mofetil in primary glomerulopathies. | Sepe, V., et al. 2008. Kidney Int. 73: 154-62. PMID: 17989649
- Proton pump inhibitors interfere with the immunosuppressive potency of mycophenolate mofetil. | Schaier, M., et al. 2010. Rheumatology (Oxford). 49: 2061-7. PMID: 20671023
- Mycophenolate mofetil-induced agranulocytosis in a renal transplant recipient. | Matsui, K., et al. 2010. Clin Exp Nephrol. 14: 637-40. PMID: 20694498
- The administration of low doses of rituximab followed by hydroxychloroquine, prednisone and low doses of mycophenolate mofetil is an effective therapy in Latin American patients with active systemic lupus erythematosus. | Galarza-Maldonado, C., et al. 2010. Autoimmun Rev. 10: 108-11. PMID: 20804861
- Effect of mycophenolate mofetil on the white blood cell count and the frequency of infection in systemic lupus erythematosus. | Subedi, A., et al. 2015. Rheumatol Int. 35: 1687-92. PMID: 25836768
- Gastrointestinal toxicity of mycophenolate mofetil in rats: Effect of administration time. | Dridi, I., et al. 2015. Chronobiol Int. 32: 1373-84. PMID: 26554521
- Lipid, monosaccharide and chitin content of cell walls of Sepedonium. | Domer, JE. and Harmon, RD. 1972. Sabouraudia. 10: 56-62. PMID: 5063164
- Effect of mycophenolate mofetil (RS-61443) on cytokine production: inhibition of superantigen-induced cytokines. | Nagy, SE., et al. 1993. Immunopharmacology. 26: 11-20. PMID: 8407281
Inhibitor of:
α-defensin 1B, β-defensin 1, β-defensin 116, β-defensin 118, β-defensin 119, β-defensin 125, β-defensin 3, AMDHD2, AUH, B lymphocytes, BTN2A1, BTN3A1, BTN3A2, BTN3A3, C10orf72, C1QDC2, C4 A, C4b, CADM1 (Cell Adhesion Molecule 1), CAP-18, CD1C, CD22, CD3-ε, CD3-ζ, CD8α, CECR1, CMV pp72, COL3A1, CRISP-8, cryptdin 13, cryptdin 15, CTPS1, DNAM-1, DSCR 2, F5 TCR α, F5 TCR β, Fcrls, GRAIL, granulysin, HISPPD2A, HLA-DP, HOTTL, ICSBP, IFN-α/βRα, IFRD2, Ig λ chain V4A, IgA, IgA chain C, Igbp1b, IgD Chain C, IgE Chain C, IgG, IgG λ light chain, IgG Fab fragment, IgG1, IgG2, IgG2a, IgG3, IgG4, IgH-VJ558, IgHg, IL-12A p35, IL-15Rα, IL-2Rα, IL-7R, ILT-11, IMPDH, IMPDH1IMPDH2, IMPDH2, ITI-H3, KIR3DL3, Klra22, La/SSB, Leukocyte Marker, Ly-49G, Ly-49N, Ly6G6e, MHC, MIC2, Might chain, NFAM1, NKp46, NT5DC2, OTTMUSG00000017373, OX2, PDZ-RhoGEF, PLA2R, PPC Synthetase, PRPS1L1, Rab 31, Rheumatoid Factor, RT1-EC2, SAA1, Scrib, Sectm1a, Serglycin, Siglec-11, Skint1, Skint11, Skint5, Skint6, Skint8, SLAMF6, T Cell Marker, T-cell receptor Vδ 2, t-GMP, TCR δ, THOC3, TPO, Trav12-1, Trav12n-1, TSARG2, and WC1.Activator of:
ADK, ADSL, AMPD2, BAF57, Bu-1a, CD137L, CD27, CD6, CTPS1, DOCK 2, EBV Ea-R p85, Fyb, GIMAP4, GIMAP5, IF3, Ig κ chain, Ig λ chain, ITPase, LAIR-1, MACHβ1, NUDT7, Respiratory Syncytial Virus, Slfn1, TREML2, and TREML4.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mycophenolate mofetil, 20 mg | sc-200971 | 20 mg | $37.00 | |||
Mycophenolate mofetil, 100 mg | sc-200971A | 100 mg | $109.00 |