JNK Inhibitor XIV MF: C28H26N8O
MW: 490.56
A selective JNK1, JNK2, and JNK3 inhibitor.

JNK Inhibitor XIV

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Nomi alternativi: SR-3306; N-(4-(3-(6-Methylpyridin-3-yl)-1H-1,2,4-triazol-1-yl)phenyl)-4-(3-morpholinophenyl)pyrimidin-2-amine
Applicazione: JNK Inhibitor XIV is a selective JNK1, JNK2, and JNK3 inhibitor
Purezza: ≥95%
Peso molecolare: 490.56
Formula molecolare: C28H26N8O
Solo per uso in Ricerca. Non previsto per Uso Diagnostico o Terapeutico.
* Vedere Certificato di Analisi per informazioni sul lotto specifico (incluso il contenuto d'acqua).
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JNK Inhibitor XIV is a cell-permeable and blood-brain-barrier-permeant anilinopyrimidine compound that acts as a highly selective, potent, reversible, and ATP-competitive JNK inhibitor (IC50 = 67, 283, and 159 nM against JNK1, JNK2, and JNK3, respectively).

Aspetto :
Powder
Stato fisico :
Solid
Solubilità :
Soluble in DMSO.
CONSERVAZIONE :
Store at 4° C
IC50 :
JNK1: IC50 = 67 nM; JNK3: IC50 = 159 nM; JNK2: IC50 = 283 nM
Solo per uso in Ricerca. Non previsto per Uso Diagnostico o Terapeutico.
PubChem CID :
SMILES :
CC1=NC=C(C=C1)C2=NN(C=N2)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC(=CC=C5)N6CCOCC6

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