Hep B cAg Antibody (1.B.315): sc-71235

Hep B cAg Antibody (1.B.315) is a mouse monoclonal IgG2a antibody that detects Hep B cAg of Hepatitis B by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Hep B cAg, or core antigen, plays a crucial role in the Hepatitis B virus life cycle as Hep B cAg encapsulates the viral genome, forming the core of the virus. This structural protein is essential for the assembly of new viral particles and serves as a key indicator of viral replication and infection status. The presence of Hep B cAg in serum is often associated with active viral replication, making Hep B cAg a vital marker for diagnosing and monitoring Hepatitis B infections. Understanding the dynamics of Hep B cAg is important for developing effective therapeutic strategies and vaccines, as Hep B cAg provides insights into the virus′s behavior and interaction with the host′s immune system. Anti-Hep B cAg antibody (1.B.315) is specifically designed to facilitate research and diagnostic applications, enabling scientists and clinicians to better understand and combat Hepatitis B virus infections.

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Hep B cAg Antibody (1.B.315) References:

1. Expression and immunoactivity of chimeric particulate antigens of receptor binding site-core antigen of hepatitis B virus.  |  Yang, HJ., et al. 2005. World J Gastroenterol. 11: 492-7. PMID: 15641132
2. Relation of hepatitis B core antigen expression with histological activity, serum HBeAg, and HBV DNA levels.  |  Sari, A., et al. 2011. Indian J Pathol Microbiol. 54: 355-8. PMID: 21623089
3. Ubiquitin conjugation of hepatitis B virus core antigen DNA vaccine leads to enhanced cell-mediated immune response in BALB/c mice.  |  Chen, JH., et al. 2011. Hepat Mon. 11: 620-8. PMID: 22140385
4. HCV core antigen testing in HIV- and HBV-coinfected patients, and in HCV-infected patients on hemodialysis.  |  Mederacke, I., et al. 2012. J Clin Virol. 53: 110-5. PMID: 22177274
5. Immune response to hepatitis B vaccination in HIV-positive adults with isolated antibodies to HBV core antigen.  |  Kaech, C., et al. 2012. J Infect. 65: 157-64. PMID: 22410383
6. Therapeutic potential of a combined hepatitis B virus surface and core antigen vaccine in patients with chronic hepatitis B.  |  Al-Mahtab, M., et al. 2013. Hepatol Int. 7: 981-9. PMID: 26202028
7. Immunohistochemical localization of hepatitis B surface antigen and hepatitis B core antigen in tissue sections. A source of false positive staining.  |  Goodman, ZD., et al. 1988. Am J Clin Pathol. 89: 533-7. PMID: 3281436
8. Antibody to hepatitis-B core antigen in patients with primary hepatic carcinoma.  |  Maupas, P., et al. 1975. Lancet. 2: 9-11. PMID: 49648
9. Application of the human hepatitis B virus core antigen from transgenic tobacco plants for serological diagnosis.  |  Tsuda, S., et al. 1998. Vox Sang. 74: 148-55. PMID: 9595641
10. Maternal antibody to hepatitis B core antigen detected in dried neonatal blood spot samples.  |  Tappin, DM., et al. 1998. Epidemiol Infect. 121: 387-90. PMID: 9825790

The preferred Hep B cAg antibody is Hep B cAg Antibody (C1-5): sc-23945.