Glutathione Antibody (1V022): sc-71155
- Glutathione Antibody (1V022) is a mouse monoclonal IgG2a, cited in 11 publications, provided at 100 µg/ml
- raised against Glutathione
- recommended for detection of Glutathione-protein complexes by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Glutathione Antibody (1V022). This work is in progress.
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Glutathione Antibody (1V022) is a mouse monoclonal IgG2a antibody that detects glutathione in non-species reactive (NSR) samples through applications such as western blotting (WB) and immunoprecipitation (IP). Glutathione is a critical tripeptide composed of glutamine, cysteine, and glycine, playing a vital role in cellular defense against oxidative stress. Anti-glutathione antibody (1V022) functions primarily as an antioxidant, neutralizing free radicals and reactive oxygen species, which can cause significant cellular damage if left unchecked. The importance of glutathione extends beyond antioxidant capabilities; glutathione also participates in various metabolic processes, including the detoxification of harmful compounds and the regulation of cellular redox status. Furthermore, glutathione exists in two forms: reduced (GSH) and oxidized (GSSG), with the reduced form being crucial for maintaining cellular health. The balance between these two forms is essential for proper cellular function, and disruptions in this balance can lead to various diseases, including neurodegenerative disorders and cancer. Glutathione monoclonal antibody (1V022) is an invaluable tool for researchers studying oxidative stress and its implications in health and disease, providing insights into the mechanisms of cellular protection and the role of glutathione in maintaining homeostasis.
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Glutathione Antibody (1V022) References:
- Coordination chemistry of glutathione. | Krezel, A. and Bal, W. 1999. Acta Biochim Pol. 46: 567-80. PMID: 10698265
- Glutathione, reduced (GSH). Monograph. | . 2001. Altern Med Rev. 6: 601-7. PMID: 11804544
- Glutathione metabolism and its role in hepatotoxicity. | DeLeve, LD. and Kaplowitz, N. 1991. Pharmacol Ther. 52: 287-305. PMID: 1820580
- Dietary modulation of the glutathione detoxification pathway and the potential for altered xenobiotic metabolism. | Smith, TK. 1991. Adv Exp Med Biol. 289: 165-9. PMID: 1897391
- Measurement of oxidized/reduced glutathione ratio. | Owen, JB. and Butterfield, DA. 2010. Methods Mol Biol. 648: 269-77. PMID: 20700719
- Oxidative Stress and Low Glutathione in Common Ear, Nose, and Throat Conditions: A Systematic Review. | Asher, BF. and Guilford, FT. 2016. Altern Ther Health Med. 22: 44-50. PMID: 27622960
- Heritability of the aged glutathione phenotype is dependent on tissue of origin. | Gould, RL., et al. 2018. Mamm Genome. 29: 619-631. PMID: 30008145
- [Plasmatic glutathione levels and their relationships with clinical and therapeutic features in patients with schizophrenia]. | Raffa, M., et al. 2021. Encephale. 47: 10-14. PMID: 33358006
- Glutathione Pulse Therapy: Promote Spatiotemporal Delivery of Reduction-Sensitive Nanoparticles at the 'Cellular Level' and Synergize PD-1 Blockade Therapy. | Dong, S., et al. 2022. Adv Sci (Weinh). 9: e2202744. PMID: 35896947
- Glutathione and glutathione delivery compounds. | Anderson, ME. 1997. Adv Pharmacol. 38: 65-78. PMID: 8895804
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glutathione Antibody (1V022) | sc-71155 | 100 µg/ml | $322.00 |