Date published: 2026-4-28

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Ginsenoside Rg1 (CAS 22427-39-0)

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Application:
Ginsenoside Rg1 is a class of triterpene saponins and steroid glycosides
CAS Number:
22427-39-0
Purity:
≥98%
Molecular Weight:
801.01
Molecular Formula:
C42H72O14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ginsenoside Rg1 is a bioactive compound categorized as a saponin, which is extensively studied in the field of plant sciences and biochemistry. Found predominantly in the Panax genus, it is a subject of interest in research on the adaptogenic properties of plants like Panax ginseng. In botanical studies, ginsenoside Rg1 is examined for its role in plant defense and its biosynthesis within ginseng species. Researchers utilize advanced analytical techniques to quantify this compound in plant extracts, studying its accumulation in response to various environmental stimuli. Moreover, in the realm of agriculture, studies focus on optimizing the conditions for cultivating ginseng plants to enhance the levels of ginsenoside Rg1 due to its significant role in plant biology. It also serves as a reference compound for the standardization and quality control of botanical preparations used in research applications.


Ginsenoside Rg1 (CAS 22427-39-0) References

  1. Ginsenoside Rg1 Inhibits Glucagon-Induced Hepatic Gluconeogenesis through Akt-FoxO1 Interaction.  |  Liu, Q., et al. 2017. Theranostics. 7: 4001-4012. PMID: 29109794
  2. Ginsenoside Rg1 promotes cerebral angiogenesis via the PI3K/Akt/mTOR signaling pathway in ischemic mice.  |  Chen, J., et al. 2019. Eur J Pharmacol. 856: 172418. PMID: 31132356
  3. Ginsenoside Rg1 attenuates cardiomyocyte apoptosis and inflammation via the TLR4/NF-kB/NLRP3 pathway.  |  Luo, M., et al. 2020. J Cell Biochem. 121: 2994-3004. PMID: 31709615
  4. Ginsenoside Rg1 Prevents PTSD-Like Behaviors in Mice Through Promoting Synaptic Proteins, Reducing Kir4.1 and TNF-α in the Hippocampus.  |  Zhang, Z., et al. 2021. Mol Neurobiol. 58: 1550-1563. PMID: 33215390
  5. Ginsenoside Rg1 alleviates acute liver injury through the induction of autophagy and suppressing NF-κB/NLRP3 inflammasome signaling pathway.  |  Zhao, J., et al. 2021. Int J Med Sci. 18: 1382-1389. PMID: 33628094
  6. Ginsenoside Rg1 promoted the wound healing in diabetic foot ulcers via miR-489-3p/Sirt1 axis.  |  Huang, L., et al. 2021. J Pharmacol Sci. 147: 271-283. PMID: 34507636
  7. Ginsenoside-Rg1 attenuates sepsis-induced cardiac dysfunction by modulating mitochondrial damage via the P2X7 receptor-mediated Akt/GSK-3β signaling pathway.  |  Liu, Z., et al. 2022. J Biochem Mol Toxicol. 36: e22885. PMID: 34859534
  8. Ginsenoside Rg1 Prevents Cognitive Impairment and Hippocampal Neuronal Apoptosis in Experimental Vascular Dementia Mice by Promoting GPR30 Expression.  |  Shen, F., et al. 2021. Neural Plast. 2021: 2412220. PMID: 34899899
  9. Ginsenoside Rg1 ameliorated experimental colitis by regulating the balance of M1/M2 macrophage polarization and the homeostasis of intestinal flora.  |  Long, J., et al. 2022. Eur J Pharmacol. 917: 174742. PMID: 34999087
  10. Ginsenoside Rg1 Reduced Microglial Activation and Mitochondrial Dysfunction to Alleviate Depression-Like Behaviour Via the GAS5/EZH2/SOCS3/NRF2 Axis.  |  Li, J., et al. 2022. Mol Neurobiol. 59: 2855-2873. PMID: 35230663
  11. Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK-3β/β-catenin signaling pathway.  |  Yang, Y., et al. 2022. Chem Biol Drug Des. 99: 884-896. PMID: 35313087
  12. Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism.  |  Cheng, H., et al. 2022. Front Immunol. 13: 817600. PMID: 35655785
  13. Ginsenoside Rg1 ameliorates sepsis-induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells.  |  Guo, J., et al. 2022. J Leukoc Biol. 112: 1065-1077. PMID: 35774015

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ginsenoside Rg1, 5 mg

sc-205708
5 mg
$265.00

Ginsenoside Rg1, 10 mg

sc-205708A
10 mg
$486.00