GID4 Antibody (B-6): sc-390887

GID4 Antibody (B-6) is a mouse monoclonal IgG3 kappa light chain antibody that detects GID4 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-GID4 antibody (B-6) is available as non-conjugated format. GID4 plays a crucial role in regulating gene expression and is involved in cellular response to stress, particularly in tumor suppression. GID4 interacts with various proteins, including tumor suppressor p53, which is essential for maintaining genomic stability and preventing malignant transformation. GID4 interaction with p53 highlights GID4′s importance in cellular pathways governing cell fate decisions, such as apoptosis and DNA repair. Dysregulation of GID4 can lead to impaired cellular responses to stress, contributing to various cancers. Chromosome 17, where GID4 is located, harbors several key genes associated with tumor suppression and genetic disorders, underscoring GID4′s significance in cancer research and therapeutic development.

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GID4 Antibody (B-6) References:

1. Birt-Hogg-Dubé Syndrome.  |  Welsch, MJ., et al. 2005. Int J Dermatol. 44: 668-73. PMID: 16101870
2. BLIMP1 regulates cell growth through repression of p53 transcription.  |  Yan, J., et al. 2007. Proc Natl Acad Sci U S A. 104: 1841-6. PMID: 17264218
3. Neurofibromatosis 1, and Not TP53, seems to be the main target of chromosome 17 deletions in de novo acute myeloid leukemia.  |  Suela, J., et al. 2007. J Clin Oncol. 25: 1151-2; author reply 1152-3. PMID: 17369586
4. Quantification of N-acetylaspartic acid in urine by LC-MS/MS for the diagnosis of Canavan disease.  |  Al-Dirbashi, OY., et al. 2007. J Inherit Metab Dis. 30: 612. PMID: 17632691
5. Susceptibility to breast cancer: hereditary syndromes and low penetrance genes.  |  Nusbaum, R., et al. Breast Dis. 27: 21-50. PMID: 17917139
6. Genetic causes of brain tumors: neurofibromatosis, tuberous sclerosis, von Hippel-Lindau, and other syndromes.  |  Farrell, CJ. and Plotkin, SR. 2007. Neurol Clin. 25: 925-46, viii. PMID: 17964021
7. Breast cancer risk among male BRCA1 and BRCA2 mutation carriers.  |  Tai, YC., et al. 2007. J Natl Cancer Inst. 99: 1811-4. PMID: 18042939
8. Novel deletion mutation in GFAP gene in an infantile form of Alexander disease.  |  Murakami, N., et al. 2008. Pediatr Neurol. 38: 50-2. PMID: 18054694
9. Strategies for ovarian cancer prevention.  |  Dann, RB., et al. 2007. Obstet Gynecol Clin North Am. 34: 667-86, viii. PMID: 18061863

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-GID4 Antibody (B-6) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-GID4 Antibody (B-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

GID4 Antibody (B-6) Specifications

Alternate Product Name: GID4

Product Clone Name: B-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 277-293

Epitope Target: GID4

Epitope Species: human

Product Reactivity/Detection: GID4

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for GID4 Antibody (B-6): P: Blocking Peptide