GH Antibody (B-10): sc-515021

GH Antibody (B-10) is a mouse monoclonal IgG1 antibody that detects growth hormone (GH) in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-GH antibody (B-10) plays a vital role in understanding the function of growth hormone, which is essential for stimulating growth, metabolism, and differentiation in various mammalian cell types. GH achieves its effects by binding to its specific receptor, growth hormone receptor (GHR), initiating a phosphorylation cascade that activates multiple signaling pathways crucial for cellular processes. The regulation of GH secretion is tightly controlled by the hypothalamic hormones GH-releasing hormone (GHRH) and somatostatin (SRIF), which work in concert to modulate GH levels in response to physiological demands. Additionally, GH secretion is influenced by feedback mechanisms involving insulin-like growth factor I, highlighting the intricate balance required for proper growth regulation. GH is synthesized in the anterior pituitary gland by acidophilic or somatotropic cells and consists of 191 amino acids, featuring two disulfide bridges that contribute to its structural stability and functional integrity. GH monoclonal antibody (B-10) provides researchers with a powerful tool for investigating the complex roles of growth hormone in various biological contexts.

The preferred GH antibody is GH Antibody (E-7): sc-374266.